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CYP2C19 Drug Metabolism Gene Test

North Dakota rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated July 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$447

Typical negotiated rate. In North Dakota, July 2026.

Insurers have agreed to pay about $447 for this service. The price depends on where it is billed: about $490 from a physician practice, and about $245 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$490$275 to $589
FacilityA hospital or hospital-owned outpatient department$245$204 to $275

How much rates vary

Facilitymedian $245 · 10th to 90th $204 to $525Professionalmedian $490 · 10th to 90th $204 to $661
$200.0$500.0$1.0Kfacility $245professional $490

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$204.17
Median
$245.47
Typical High
$524.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$204.17
Typical High
$870.96
BCBS
Setting
Professional
Modifier
Global
Typical Low
$380.19
Median
$562.34
Typical High
$660.69
Cigna
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$416.87
Medica
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$208.93
Typical High
$524.81
Medica
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$346.74
Typical High
$588.84
United
Setting
Facility
Modifier
Global
Typical Low
$776.25
Median
$776.25
Typical High
$776.25
United
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$295.12
Typical High
$446.68

Where North Dakota sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

North Dakota $447 · 3rd of 51
AK $661VT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.