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Tissue Marker Measurement, Manual Method

Nationwide rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

Facilitymedian $44 · 10th–90th $25$2000%20%10th90th$44Professionalmedian $68 · 10th–90th $23$2000%10%10th90th$68$0.5$5.0$50.0$500.0$5.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$25.12
Median
$30.20
Typical High
$81.28
Aetna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$93.33
Typical High
$204.17
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.05
Median
$25.70
Typical High
$64.57
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$45.71
Median
$66.07
Typical High
$147.91
BCBS
Setting
Professional
Modifier
Global
Typical Low
$44.67
Median
$70.79
Typical High
$229.09
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.49
Median
$23.99
Typical High
$66.07
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$30.90
Median
$46.77
Typical High
$173.78
Cigna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$8.13
Median
$38.02
Typical High
$64.57
Cigna
Setting
Professional
Modifier
Global
Typical Low
$37.15
Median
$85.11
Typical High
$218.78
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$26.92
Typical High
$60.26
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$24.55
Median
$57.54
Typical High
$165.96
United
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$107.15
Typical High
$245.47
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.60
Median
$33.88
Typical High
$100.00
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$39.81
Median
$74.13
Typical High
$181.97