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Tissue Marker Measurement, Manual Method

Virginia rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated October 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$91.20

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $91.20 for this service. The price depends on where it is billed: about $87.10 from a physician practice, and about $115 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$87.10$50.12 to $117
FacilityA hospital or hospital-owned outpatient department$115$61.66 to $214

How much rates vary

Facilitymedian $115 · 10th to 90th $35 to $427Professionalmedian $87 · 10th to 90th $45 to $158
$20$100$500$2K$10Kfacility $115professional $87

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$95.50
Median
$109.65
Typical High
$109.65
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$95.50
Median
$109.65
Typical High
$114.82
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$25.12
Median
$26.92
Typical High
$34.67
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$66.07
Median
$83.18
Typical High
$83.18
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$416.87
Typical High
$524.81
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$44.67
Median
$44.67
Typical High
$70.79
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.49
Median
$13.49
Typical High
$21.38
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$30.90
Median
$30.90
Typical High
$48.98
CareFirst
Setting
Professional
Modifier
None (both parts)
Typical Low
$91.20
Median
$120.23
Typical High
$134.90
CareFirst
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.18
Median
$31.62
Typical High
$37.15
Cigna
Setting
Facility
Modifier
None
Typical Low
$95.50
Median
$165.96
Typical High
$275.42
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$40.74
Median
$66.07
Typical High
$181.97
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$16.60
Typical High
$50.12
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$27.54
Median
$51.29
Typical High
$128.82
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$147.91
Typical High
$177.83
Medcost
Setting
Facility
Modifier
None
Typical Low
$97.72
Median
$97.72
Typical High
$199.53
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$24.55
Median
$24.55
Typical High
$102.33
Sentara
Setting
Facility
Modifier
None
Typical Low
$28.84
Median
$89.13
Typical High
$302.00
Sentara
Setting
Professional
Modifier
None (both parts)
Typical Low
$37.15
Median
$85.11
Typical High
$213.80
Sentara
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.84
Median
$32.36
Typical High
$69.18
Sentara
Setting
Professional
Modifier
TC · Technical part
Typical Low
$54.95
Median
$63.10
Typical High
$194.98
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$56.23
Median
$114.82
Typical High
$223.87
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$17.38
Median
$33.88
Typical High
$67.61
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$38.90
Median
$77.62
Typical High
$158.49
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$47.86
Median
$54.95
Typical High
$54.95
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$19.05
Median
$21.88
Typical High
$21.88

Where Virginia sits

The same service costs 4.6 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 45th of 51

$91.20

AK $269AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.