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Tissue Marker Measurement, Manual Method

Mississippi rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated October 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$123

Typical negotiated rate. In Mississippi, October 2026.

Insurers have agreed to pay about $123 for this service. Most negotiated rates run $60.26 to $158.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $65 · 10th to 90th $55 to $200Professionalmedian $123 · 10th to 90th $35 to $200
$50$100$200facility $65professional $123

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$120.23
Median
$120.23
Typical High
$199.53
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$120.23
Median
$199.53
Typical High
$223.87
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$54.95
Typical High
$61.66
BCBS Mississippi
Setting
Professional
Modifier
None (both parts)
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$54.95
Median
$57.54
Typical High
$64.57
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$51.29
Median
$83.18
Typical High
$162.18
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$33.11
Median
$33.11
Typical High
$33.11
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$56.23
Median
$117.49
Typical High
$186.21
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.05
Median
$33.88
Typical High
$57.54
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$35.48
Median
$83.18
Typical High
$141.25
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$58.88
Median
$100.00
Typical High
$112.20
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$23.99
Median
$39.81
Typical High
$45.71

Where Mississippi sits

The same service costs 4.6 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Mississippi· 23rd of 51

$123

AK $269AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.