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Tissue Marker Measurement, Manual Method

Iowa rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated October 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$158

Typical negotiated rate. In Iowa, October 2026.

Insurers have agreed to pay about $158 for this service. The price depends on where it is billed: about $158 from a physician practice, and about $174 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$158$69.18 to $229
FacilityA hospital or hospital-owned outpatient department$174$129 to $245

How much rates vary

Facilitymedian $174 · 10th to 90th $87 to $302Professionalmedian $158 · 10th to 90th $56 to $275
$50$100$200$500facility $174professional $158

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$87.10
Median
$173.78
Typical High
$263.03
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$85.11
Median
$91.20
Typical High
$147.91
Cigna
Setting
Facility
Modifier
None
Typical Low
$245.47
Median
$245.47
Typical High
$245.47
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$70.79
Median
$234.42
Typical High
$275.42
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.44
Median
$57.54
Typical High
$85.11
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$47.86
Median
$173.78
Typical High
$186.21
Hally Health
Setting
Professional
Modifier
None
Typical Low
$100.00
Median
$177.83
Typical High
$389.05
Medica
Setting
Facility
Modifier
None
Typical Low
$87.10
Median
$147.91
Typical High
$309.03
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$107.15
Median
$229.09
Typical High
$724.44
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$89.13
Typical High
$199.53
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$74.13
Median
$199.53
Typical High
$537.03
Midlands
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$234.42
Typical High
$316.23
Midlands
Setting
Facility
Modifier
None
Typical Low
$245.47
Median
$245.47
Typical High
$245.47
Midlands
Setting
Professional
Modifier
None (both parts)
Typical Low
$208.93
Median
$208.93
Typical High
$251.19
Oscar Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$35.48
Median
$128.82
Typical High
$257.04
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$107.15
Median
$117.49
Typical High
$251.19
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$34.67
Typical High
$79.43
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$74.13
Median
$83.18
Typical High
$173.78
Wellmark
Setting
Professional
Modifier
None (both parts)
Typical Low
$269.15
Median
$288.40
Typical High
$309.03
Wellmark
Setting
Professional
Modifier
26 · Professional part
Typical Low
$67.61
Median
$72.44
Typical High
$77.62
Wellmark
Setting
Professional
Modifier
TC · Technical part
Typical Low
$204.17
Median
$213.80
Typical High
$229.09

Where Iowa sits

The same service costs 4.6 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 15th of 51

$158

AK $269AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.