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Tissue Marker Measurement, Manual Method

Iowa rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$115

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $115 for this service. Most negotiated rates run $87.10 to $195.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $115 · 10th to 90th $35 to $257
$50$100$200professional $115

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$102.33
Typical High
$114.82
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$28.18
Typical High
$30.90
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$63.10
Median
$75.86
Typical High
$83.18
Cigna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$8.13
Median
$38.02
Typical High
$53.70
Cigna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$190.55
Typical High
$275.42
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.05
Median
$57.54
Typical High
$83.18
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$38.02
Median
$131.83
Typical High
$181.97
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$208.93
Typical High
$389.05
Hally Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$54.95
Typical High
$204.17
Hally Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$74.13
Median
$131.83
Typical High
$186.21
Medica
Setting
Facility
Modifier
26 · Professional part
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
Medica
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$186.21
Typical High
$724.44
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$25.70
Median
$51.29
Typical High
$199.53
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$44.67
Median
$95.50
Typical High
$537.03
Midlands
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$190.55
Typical High
$275.42
Midlands
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$57.54
Typical High
$97.72
Midlands
Setting
Professional
Modifier
TC · Technical part
Typical Low
$87.10
Median
$131.83
Typical High
$173.78
Midlands
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Midlands
Setting
Professional
Modifier
26 · Professional part
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
Midlands
Setting
Professional
Modifier
TC · Technical part
Typical Low
$144.54
Median
$144.54
Typical High
$144.54
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$33.88
Median
$120.23
Typical High
$239.88
United
Setting
Professional
Modifier
Global
Typical Low
$102.33
Median
$117.49
Typical High
$281.84
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$60.26
Typical High
$104.71
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$70.79
Median
$83.18
Typical High
$199.53
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$269.15
Typical High
$295.12
Wellmark
Setting
Professional
Modifier
26 · Professional part
Typical Low
$57.54
Median
$67.61
Typical High
$72.44
Wellmark
Setting
Professional
Modifier
TC · Technical part
Typical Low
$173.78
Median
$204.17
Typical High
$218.78

Where Iowa sits

The same service costs 4.6 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 19th of 51

$115

MN $263RI $57.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.