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Tissue Marker Measurement, Manual Method

Missouri rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$102

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $102 for this service. Most negotiated rates run $74.13 to $158.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $102 · 10th to 90th $46 to $224
$50$100$200$500professional $102

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$102.33
Typical High
$165.96
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.99
Median
$28.18
Typical High
$58.88
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$46.77
Median
$75.86
Typical High
$131.83
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.38
Median
$21.38
Typical High
$42.66
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$29.51
Median
$75.86
Typical High
$194.98
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.00
Median
$26.30
Typical High
$53.70
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$19.50
Median
$47.86
Typical High
$141.25
BCBS
Setting
Professional
Modifier
Global
Typical Low
$83.18
Median
$117.49
Typical High
$208.93
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.84
Median
$31.62
Typical High
$53.70
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$79.43
Median
$87.10
Typical High
$177.83
Cigna
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$64.57
Typical High
$199.53
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.59
Median
$16.60
Typical High
$64.57
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$23.44
Median
$45.71
Typical High
$131.83
Medica
Setting
Facility
Modifier
26 · Professional part
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
Medica
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$114.82
Typical High
$724.44
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.42
Median
$33.88
Typical High
$199.53
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$47.86
Median
$79.43
Typical High
$537.03
United
Setting
Professional
Modifier
Global
Typical Low
$67.61
Median
$112.20
Typical High
$234.42
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.42
Median
$33.88
Typical High
$70.79
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$48.98
Median
$77.62
Typical High
$173.78

Where Missouri sits

The same service costs 4.6 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 28th of 51

$102

MN $263RI $57.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.