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Tissue Marker Measurement, Manual Method

Illinois rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$105

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $105 for this service. Most negotiated rates run $72.44 to $145.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $105 · 10th to 90th $45 to $191
$50$100$200professional $105

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$89.13
Median
$89.13
Typical High
$89.13
Aetna
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$104.71
Typical High
$169.82
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.91
Median
$27.54
Typical High
$56.23
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$48.98
Median
$77.62
Typical High
$120.23
BCBS
Setting
Professional
Modifier
Global
Typical Low
$36.31
Median
$100.00
Typical High
$204.17
Cigna
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$64.57
Typical High
$208.93
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.49
Median
$16.60
Typical High
$53.70
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$27.54
Median
$48.98
Typical High
$158.49
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$218.78
Typical High
$467.74
Hally Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$36.31
Median
$56.23
Typical High
$263.03
Hally Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$89.13
Median
$144.54
Typical High
$263.03
Molina
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$32.36
Typical High
$33.11
United
Setting
Professional
Modifier
Global
Typical Low
$67.61
Median
$109.65
Typical High
$194.98
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.89
Median
$37.15
Typical High
$100.00
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$47.86
Median
$74.13
Typical High
$141.25

Where Illinois sits

The same service costs 4.6 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 24th of 51

$105

MN $263RI $57.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.