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Tissue Marker Measurement, Manual Method

Florida rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated October 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$89.13

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $89.13 for this service. The price depends on where it is billed: about $85.11 from a physician practice, and about $102 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$85.11$66.07 to $129
FacilityA hospital or hospital-owned outpatient department$102$66.07 to $174

How much rates vary

Facilitymedian $102 · 10th to 90th $42 to $389Professionalmedian $85 · 10th to 90th $45 to $170
$50$100$200$500facility $102professional $85

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$46.77
Median
$66.07
Typical High
$173.78
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$46.77
Median
$66.07
Typical High
$93.33
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.22
Median
$20.42
Typical High
$25.70
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$30.20
Median
$45.71
Typical High
$67.61
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$56.23
Median
$56.23
Typical High
$56.23
AvMed
Setting
Facility
Modifier
None
Typical Low
$93.33
Median
$123.03
Typical High
$229.09
AvMed
Setting
Professional
Modifier
None (both parts)
Typical Low
$74.13
Median
$93.33
Typical High
$134.90
Cigna
Setting
Facility
Modifier
None
Typical Low
$31.62
Median
$63.10
Typical High
$389.05
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$37.15
Median
$67.61
Typical High
$154.88
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.18
Median
$19.50
Typical High
$48.98
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$24.55
Median
$47.86
Typical High
$109.65
Florida Blue
Setting
Professional
Modifier
None (both parts)
Typical Low
$52.48
Median
$81.28
Typical High
$169.82
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$42.66
Median
$109.65
Typical High
$173.78
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$44.67
Median
$69.18
Typical High
$234.42
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.49
Median
$20.42
Typical High
$67.61
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$29.51
Median
$50.12
Typical High
$165.96
Wellpoint
Setting
Professional
Modifier
None (both parts)
Typical Low
$69.18
Median
$69.18
Typical High
$125.89
Wellpoint
Setting
Professional
Modifier
26 · Professional part
Typical Low
$17.38
Median
$17.38
Typical High
$31.62
Wellpoint
Setting
Professional
Modifier
TC · Technical part
Typical Low
$52.48
Median
$52.48
Typical High
$93.33
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$23.44
Median
$33.11
Typical High
$44.67
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$9.33
Median
$13.18
Typical High
$18.20

Where Florida sits

The same service costs 4.6 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 47th of 51

$89.13

AK $269AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.