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Tissue Marker Measurement, Manual Method

Nebraska rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

Professionalmedian $76 · 10th–90th $21$2040%10%10th90th$76$20.0$50.0$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$75.86
Median
$75.86
Typical High
$169.82
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.89
Median
$20.89
Typical High
$46.77
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$54.95
Median
$54.95
Typical High
$194.98
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.49
Median
$15.49
Typical High
$15.49
BCBS
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$190.55
Typical High
$194.98
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$34.67
Median
$51.29
Typical High
$51.29
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$95.50
Median
$141.25
Typical High
$144.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$223.87
Typical High
$316.23
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$45.71
Median
$58.88
Typical High
$83.18
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$109.65
Median
$165.96
Typical High
$234.42
Medica
Setting
Professional
Modifier
Global
Typical Low
$67.61
Median
$114.82
Typical High
$724.44
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$33.11
Typical High
$199.53
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$43.65
Median
$83.18
Typical High
$537.03
Midlands
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$229.09
Typical High
$316.23
Midlands
Setting
Professional
Modifier
26 · Professional part
Typical Low
$56.23
Median
$60.26
Typical High
$83.18
Midlands
Setting
Professional
Modifier
TC · Technical part
Typical Low
$131.83
Median
$169.82
Typical High
$234.42
Midlands
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$295.12
Typical High
$316.23
Midlands
Setting
Professional
Modifier
26 · Professional part
Typical Low
$70.79
Median
$75.86
Typical High
$83.18
Midlands
Setting
Professional
Modifier
TC · Technical part
Typical Low
$186.21
Median
$218.78
Typical High
$234.42
United
Setting
Professional
Modifier
Global
Typical Low
$67.61
Median
$112.20
Typical High
$208.93
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$33.11
Typical High
$72.44
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$44.67
Median
$79.43
Typical High
$147.91