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Tissue Marker Measurement, Manual Method

Massachusetts rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$170

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $170 for this service. Most negotiated rates run $74.13 to $302.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $170 · 10th to 90th $58 to $407
$50$100$200$500$1Kprofessional $170

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$67.61
Typical High
$436.52
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$18.20
Median
$20.42
Typical High
$100.00
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$39.81
Median
$48.98
Typical High
$331.13
AllWays Health Partners
Setting
Facility
Modifier
26 · Professional part
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$79.43
Median
$162.18
Typical High
$724.44
AllWays Health Partners
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.88
Median
$43.65
Typical High
$199.53
AllWays Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$58.88
Median
$123.03
Typical High
$537.03
BCBS
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$162.18
Typical High
$162.18
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$45.71
Median
$64.57
Typical High
$87.10
Cigna
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$109.65
Typical High
$239.88
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.60
Median
$30.90
Typical High
$66.07
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$44.67
Median
$75.86
Typical High
$177.83
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$138.04
Typical High
$234.42
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$275.42
Typical High
$371.54
Harvard Pilgrim
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.90
Median
$67.61
Typical High
$89.13
Harvard Pilgrim
Setting
Professional
Modifier
TC · Technical part
Typical Low
$117.49
Median
$199.53
Typical High
$275.42
Mass General Brigham
Setting
Facility
Modifier
26 · Professional part
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$79.43
Median
$162.18
Typical High
$724.44
Mass General Brigham
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.88
Median
$43.65
Typical High
$199.53
Mass General Brigham
Setting
Professional
Modifier
TC · Technical part
Typical Low
$58.88
Median
$123.03
Typical High
$537.03
United
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$173.78
Typical High
$389.05
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.88
Median
$47.86
Typical High
$91.20
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$58.88
Median
$128.82
Typical High
$295.12

Where Massachusetts sits

The same service costs 4.6 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 10th of 51

$170

MN $263RI $57.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.