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Tissue Marker Measurement, Manual Method

South Carolina rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated October 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$105

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $105 for this service. The price depends on where it is billed: about $102 from a physician practice, and about $195 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$102$69.18 to $126
FacilityA hospital or hospital-owned outpatient department$195$126 to $427

How much rates vary

Facilitymedian $195 · 10th to 90th $89 to $589Professionalmedian $102 · 10th to 90th $36 to $155
$50$100$200$500facility $195professional $102

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$89.13
Median
$89.13
Typical High
$89.13
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$89.13
Median
$89.13
Typical High
$93.33
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$24.55
Typical High
$27.54
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$63.10
Median
$64.57
Typical High
$66.07
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$562.34
Typical High
$575.44
BCBS South Carolina
Setting
Professional
Modifier
None (both parts)
Typical Low
$117.49
Median
$120.23
Typical High
$151.36
BCBS South Carolina
Setting
Professional
Modifier
26 · Professional part
Typical Low
$31.62
Median
$44.67
Typical High
$57.54
BCBS South Carolina
Setting
Professional
Modifier
TC · Technical part
Typical Low
$72.44
Median
$89.13
Typical High
$93.33
Cigna
Setting
Facility
Modifier
None
Typical Low
$177.83
Median
$239.88
Typical High
$588.84
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$34.67
Median
$36.31
Typical High
$102.33
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.30
Median
$12.88
Typical High
$36.31
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$22.39
Median
$23.44
Typical High
$66.07
Medcost
Setting
Facility
Modifier
None
Typical Low
$89.13
Median
$107.15
Typical High
$338.84
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$102.33
Median
$102.33
Typical High
$138.04
Medcost
Setting
Professional
Modifier
26 · Professional part
Typical Low
$36.31
Median
$36.31
Typical High
$54.95
Medcost
Setting
Professional
Modifier
TC · Technical part
Typical Low
$66.07
Median
$66.07
Typical High
$144.54
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$33.11
Median
$107.15
Typical High
$162.18
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$61.66
Median
$93.33
Typical High
$186.21
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.85
Median
$32.36
Typical High
$66.07
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$42.66
Median
$60.26
Typical High
$131.83
5 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$51.29
Median
$51.29
Typical High
$85.11
Medcost
Setting
Professional
Modifier
80 · Assistant surgeon
Typical Low
$20.42
Median
$20.42
Typical High
$33.88
Medcost
Setting
Professional
Modifier
81 · Minimal assistant surgeon
Typical Low
$14.45
Median
$14.45
Typical High
$23.99
Medcost
Setting
Professional
Modifier
82 · Assistant surgeon, no resident
Typical Low
$14.45
Median
$14.45
Typical High
$23.99
Medcost
Setting
Professional
Modifier
AS · PA/NP assist
Typical Low
$14.45
Median
$14.45
Typical High
$23.99

Where South Carolina sits

The same service costs 4.6 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 34th of 51

$105

AK $269AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.