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Tissue Marker Measurement, Manual Method

Maine rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$178

Typical negotiated rate. In Maine, July 2026.

Insurers have agreed to pay about $178 for this service. Most negotiated rates run $93.33 to $245.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $178 · 10th to 90th $93 to $363
$50$100$200$500professional $178

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$93.33
Median
$93.33
Typical High
$93.33
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$27.54
Median
$27.54
Typical High
$27.54
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$67.61
Median
$67.61
Typical High
$95.50
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$44.67
Median
$181.97
Typical High
$245.47
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$47.86
Typical High
$61.66
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$30.90
Median
$131.83
Typical High
$181.97
Cigna
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$93.33
Typical High
$141.25
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$0.35
Median
$32.36
Typical High
$42.66
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$1.12
Median
$70.79
Typical High
$100.00
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$194.98
Typical High
$363.08
Harvard Pilgrim
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$48.98
Typical High
$91.20
Harvard Pilgrim
Setting
Professional
Modifier
TC · Technical part
Typical Low
$120.23
Median
$147.91
Typical High
$275.42
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$93.33
Median
$93.33
Typical High
$154.88
Martin's Point
Setting
Professional
Modifier
26 · Professional part
Typical Low
$27.54
Median
$27.54
Typical High
$39.81
Martin's Point
Setting
Professional
Modifier
TC · Technical part
Typical Low
$67.61
Median
$95.50
Typical High
$114.82
United
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$186.21
Typical High
$363.08
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$48.98
Typical High
$91.20
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$70.79
Median
$123.03
Typical High
$275.42

Where Maine sits

The same service costs 4.6 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 9th of 51

$178

MN $263RI $57.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.