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Tissue Marker Measurement, Manual Method

Alabama rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated October 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$58.88

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $58.88 for this service. The price depends on where it is billed: about $69.18 from a physician practice, and about $58.88 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$69.18$53.70 to $129
FacilityA hospital or hospital-owned outpatient department$58.88$58.88 to $58.88

How much rates vary

Facilitymedian $59 · 10th to 90th $59 to $78Professionalmedian $69 · 10th to 90th $34 to $129
$50$100$200$500facility $59professional $69

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$95.50
Median
$95.50
Typical High
$95.50
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$85.11
Median
$128.82
Typical High
$128.82
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$24.55
Median
$35.48
Typical High
$35.48
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$61.66
Median
$95.50
Typical High
$95.50
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31 + 55 · Aftercare only + 99 · Multiple modifiers
Typical Low
$33.11
Median
$69.18
Typical High
$102.33
Cigna
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$77.62
Typical High
$302.00
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$33.88
Median
$33.88
Typical High
$87.10
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.02
Median
$12.02
Typical High
$43.65
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$21.38
Median
$21.38
Typical High
$56.23
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$58.88
Median
$69.18
Typical High
$117.49
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$21.88
Typical High
$33.88
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$37.15
Median
$46.77
Typical High
$83.18
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$41.69
Median
$64.57
Typical High
$64.57
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$16.60
Median
$25.70
Typical High
$25.70

Where Alabama sits

The same service costs 4.6 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 51st of 51

$58.88

AK $269AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.