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Tissue Marker Measurement, Manual Method

Colorado rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$100

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $100 for this service. Most negotiated rates run $77.62 to $129.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $100 · 10th to 90th $65 to $209
$50$100$200professional $100

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$95.50
Typical High
$128.82
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.42
Median
$24.55
Typical High
$33.88
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$45.71
Median
$69.18
Typical High
$95.50
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$128.82
Typical High
$218.78
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$33.11
Typical High
$56.23
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$95.50
Median
$95.50
Typical High
$162.18
Cigna
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$66.07
Typical High
$204.17
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.22
Median
$18.62
Typical High
$54.95
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$21.88
Median
$50.12
Typical High
$165.96
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$190.55
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$45.71
Median
$45.71
Typical High
$45.71
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$144.54
Median
$144.54
Typical High
$144.54
Select Health
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$169.82
Typical High
$331.13
Select Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$40.74
Typical High
$81.28
Select Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$85.11
Median
$128.82
Typical High
$251.19
United
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$77.62
Typical High
$218.78
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.85
Median
$30.20
Typical High
$79.43
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$30.90
Median
$57.54
Typical High
$158.49

Where Colorado sits

The same service costs 4.6 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 29th of 51

$100

MN $263RI $57.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.