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Tissue Marker Measurement, Manual Method

Colorado rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated October 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$166

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $166 for this service. The price depends on where it is billed: about $155 from a physician practice, and about $209 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$155$91.20 to $251
FacilityA hospital or hospital-owned outpatient department$209$100 to $269

How much rates vary

Facilitymedian $209 · 10th to 90th $62 to $389Professionalmedian $155 · 10th to 90th $49 to $407
$50$100$200$500facility $209professional $155

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$66.07
Median
$100.00
Typical High
$128.82
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$229.09
Typical High
$407.38
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$128.82
Median
$251.19
Typical High
$436.52
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$63.10
Typical High
$112.20
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$95.50
Median
$186.21
Typical High
$323.59
Cigna
Setting
Facility
Modifier
None
Typical Low
$54.95
Median
$100.00
Typical High
$302.00
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$33.11
Median
$60.26
Typical High
$204.17
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.22
Median
$16.22
Typical High
$60.26
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$21.88
Median
$45.71
Typical High
$151.36
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$165.96
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$162.18
Median
$194.98
Typical High
$524.81
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$46.77
Typical High
$128.82
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$123.03
Median
$147.91
Typical High
$389.05
Select Health
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$251.19
Typical High
$288.40
Select Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$112.20
Median
$120.23
Typical High
$331.13
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$44.67
Median
$77.62
Typical High
$234.42
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.14
Median
$20.42
Typical High
$67.61
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$29.51
Median
$57.54
Typical High
$165.96

Where Colorado sits

The same service costs 4.6 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 13th of 51

$166

AK $269AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.