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Tissue Marker Measurement, Manual Method

Maryland rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$107

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $107 for this service. Most negotiated rates run $85.11 to $117.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $107 · 10th to 90th $49 to $138
$50$100$200professional $107

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$97.72
Typical High
$109.65
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.22
Median
$26.92
Typical High
$28.18
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$30.20
Median
$72.44
Typical High
$83.18
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$120.23
Typical High
$147.91
CareFirst
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$28.18
Typical High
$35.48
CareFirst
Setting
Professional
Modifier
TC · Technical part
Typical Low
$85.11
Median
$91.20
Typical High
$109.65
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1.48
Median
$67.61
Typical High
$208.93
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$0.35
Median
$17.38
Typical High
$54.95
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$1.12
Median
$51.29
Typical High
$165.96
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$165.96
Typical High
$213.80
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$39.81
Typical High
$50.12
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$104.71
Median
$125.89
Typical High
$158.49
United
Setting
Professional
Modifier
Global
Typical Low
$52.48
Median
$100.00
Typical High
$165.96
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.60
Median
$31.62
Typical High
$61.66
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$35.48
Median
$74.13
Typical High
$114.82
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$97.72
Median
$194.98
Typical High
$213.80
Wellpoint
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.18
Median
$45.71
Typical High
$50.12
Wellpoint
Setting
Professional
Modifier
TC · Technical part
Typical Low
$69.18
Median
$147.91
Typical High
$165.96

Where Maryland sits

The same service costs 4.6 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 23rd of 51

$107

MN $263RI $57.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.