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Tissue Marker Measurement, Manual Method

Indiana rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated October 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$93.33

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $93.33 for this service. The price depends on where it is billed: about $72.44 from a physician practice, and about $186 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$72.44$34.67 to $117
FacilityA hospital or hospital-owned outpatient department$186$107 to $355

How much rates vary

Facilitymedian $186 · 10th to 90th $62 to $468Professionalmedian $72 · 10th to 90th $35 to $174
$50$100$200$500$1K$2Kfacility $186professional $72

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$93.33
Median
$104.71
Typical High
$147.91
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$89.13
Median
$93.33
Typical High
$223.87
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$25.12
Median
$25.70
Typical High
$56.23
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$63.10
Median
$67.61
Typical High
$77.62
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$34.67
Median
$66.07
Typical High
$467.74
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$34.67
Median
$34.67
Typical High
$120.23
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.30
Median
$12.30
Typical High
$30.90
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$22.39
Median
$22.39
Typical High
$89.13
CareSource
Setting
Facility
Modifier
None
Typical Low
$33.88
Median
$91.20
Typical High
$125.89
Cigna
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$107.15
Typical High
$269.15
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$34.67
Median
$70.79
Typical High
$186.21
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.30
Median
$23.44
Typical High
$64.57
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$22.39
Median
$47.86
Typical High
$128.82
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$354.81
Typical High
$2,089.30
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None (both parts)
Typical Low
$131.83
Median
$165.96
Typical High
$218.78
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.88
Median
$43.65
Typical High
$58.88
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
TC · Technical part
Typical Low
$89.13
Median
$123.03
Typical High
$162.18
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$64.57
Median
$107.15
Typical High
$199.53
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$33.88
Typical High
$57.54
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$43.65
Median
$75.86
Typical High
$138.04
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$45.71
Median
$46.77
Typical High
$54.95
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$18.62
Median
$18.62
Typical High
$21.88

Where Indiana sits

The same service costs 4.6 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 43rd of 51

$93.33

AK $269AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.