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Tissue Marker Measurement, Manual Method

Minnesota rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$263

Typical negotiated rate. In Minnesota, July 2026.

Insurers have agreed to pay about $263 for this service. Most negotiated rates run $174 to $380.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $263 · 10th to 90th $117 to $447
$100$200$500professional $263

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$30.20
Median
$30.20
Typical High
$30.20
Aetna
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$117.49
Typical High
$436.52
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$22.91
Median
$30.20
Typical High
$100.00
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$57.54
Median
$87.10
Typical High
$331.13
BCBS
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$331.13
Typical High
$478.63
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$52.48
Median
$83.18
Typical High
$120.23
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$158.49
Median
$263.03
Typical High
$363.08
Cigna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$54.95
Median
$275.42
Typical High
$331.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$218.78
Typical High
$281.84
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$43.65
Median
$54.95
Typical High
$70.79
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$131.83
Median
$165.96
Typical High
$213.80
Health Partners
Setting
Facility
Modifier
26 · Professional part
Typical Low
$42.66
Median
$263.03
Typical High
$263.03
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$257.04
Health Partners
Setting
Professional
Modifier
26 · Professional part
Typical Low
$42.66
Median
$42.66
Typical High
$69.18
Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$125.89
Median
$128.82
Typical High
$190.55
Medica
Setting
Facility
Modifier
26 · Professional part
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
Medica
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$194.98
Typical High
$724.44
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.42
Median
$66.07
Typical High
$199.53
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$50.12
Median
$134.90
Typical High
$537.03
United
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$239.88
Typical High
$446.68
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.88
Median
$95.50
Typical High
$165.96
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$181.97
Typical High
$338.84

Where Minnesota sits

The same service costs 4.6 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 1st of 51

$263

MN $263RI $57.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.