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Tissue Marker Measurement, Manual Method

Michigan rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated October 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$145

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $145 for this service. The price depends on where it is billed: about $145 from a physician practice, and about $158 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$145$79.43 to $200
FacilityA hospital or hospital-owned outpatient department$158$120 to $200

How much rates vary

Facilitymedian $158 · 10th to 90th $115 to $288Professionalmedian $145 · 10th to 90th $55 to $214
$10$20$50$100$200$500facility $158professional $145

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$112.20
Median
$112.20
Typical High
$114.82
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$79.43
Median
$83.18
Typical High
$162.18
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$112.20
Median
$125.89
Typical High
$125.89
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.20
Median
$32.36
Typical High
$32.36
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$95.50
Typical High
$95.50
BCBS
Setting
Facility
Modifier
None
Typical Low
$120.23
Median
$173.78
Typical High
$295.12
BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$141.25
Median
$199.53
Typical High
$213.80
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$52.48
Median
$52.48
Typical High
$52.48
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$158.49
Median
$158.49
Typical High
$158.49
CareSource
Setting
Facility
Modifier
None
Typical Low
$131.83
Median
$131.83
Typical High
$131.83
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$34.67
Median
$64.57
Typical High
$177.83
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$147.91
Typical High
$162.18
Health Alliance Plan
Setting
Facility
Modifier
TC · Technical part
Typical Low
$79.43
Median
$97.72
Typical High
$162.18
Health Alliance Plan
Setting
Professional
Modifier
None (both parts)
Typical Low
$54.95
Median
$79.43
Typical High
$144.54
Health Alliance Plan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$18.62
Median
$27.54
Typical High
$40.74
Health Alliance Plan
Setting
Professional
Modifier
TC · Technical part
Typical Low
$36.31
Median
$53.70
Typical High
$104.71
Priority Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$34.67
Median
$56.23
Typical High
$165.96
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$46.77
Median
$79.43
Typical High
$169.82
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.85
Median
$26.92
Typical High
$53.70
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$30.90
Median
$54.95
Typical High
$114.82
8 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$38.90
Median
$48.98
Typical High
$81.28
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$15.85
Median
$19.50
Typical High
$33.11
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$56.23
Median
$63.10
Typical High
$63.10
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$22.39
Median
$25.70
Typical High
$25.70
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$38.90
Median
$46.77
Typical High
$81.28
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$15.85
Median
$19.05
Typical High
$33.11
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$54.95
Median
$72.44
Typical High
$72.44
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$21.88
Median
$28.84
Typical High
$28.84

Where Michigan sits

The same service costs 4.6 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 19th of 51

$145

AK $269AL $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.