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Tissue Marker Measurement, Manual Method

North Carolina rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

How much does Tissue Marker Measurement, Manual Method cost?

$89.13

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $89.13 for this service. Most negotiated rates run $77.62 to $110.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $89 · 10th to 90th $72 to $200
$50$100$200$500professional $89

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$20.89
Median
$27.54
Typical High
$47.86
Aetna
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$89.13
Typical High
$144.54
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.38
Median
$25.12
Typical High
$41.69
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$53.70
Median
$63.10
Typical High
$104.71
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.18
Median
$44.67
Typical High
$47.86
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$63.10
Median
$83.18
Typical High
$112.20
Cigna
Setting
Professional
Modifier
Global
Typical Low
$36.31
Median
$60.26
Typical High
$162.18
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$16.60
Typical High
$46.77
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$23.44
Median
$44.67
Typical High
$123.03
Medcost
Setting
Professional
Modifier
Global
Typical Low
$24.55
Median
$24.55
Typical High
$24.55
United
Setting
Professional
Modifier
Global
Typical Low
$48.98
Median
$74.13
Typical High
$186.21
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$18.62
Median
$30.20
Typical High
$67.61
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$31.62
Median
$53.70
Typical High
$128.82
Wellcare
Setting
Facility
Modifier
26 · Professional part
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$724.44
Median
$724.44
Typical High
$1,096.48
Wellcare
Setting
Professional
Modifier
26 · Professional part
Typical Low
$199.53
Median
$199.53
Typical High
$263.03
Wellcare
Setting
Professional
Modifier
TC · Technical part
Typical Low
$537.03
Median
$537.03
Typical High
$831.76

Where North Carolina sits

The same service costs 4.6 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 41st of 51

$89.13

MN $263RI $57.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.