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Tissue Marker Measurement, Manual Method

North Carolina rates for HCPCS 88369

This laboratory service is an additional measurement performed on a tissue sample already being analyzed under a microscope, with a pathologist visually counting and scoring the result rather than using computer-assisted image analysis, to quantify how much of a specific marker is present. It's used to help characterize a tumor in more detail and can guide decisions about treatment. It's billed in addition to the main tissue analysis rather than as a stand-alone test.

Rates data updated July 2026.

Facilitymedian $28 · 10th–90th $21$480%50%10th90th$28Professionalmedian $63 · 10th–90th $25$1100%5%10%10th90th$63$20.0$50.0$100.0$200.0$500.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$20.89
Median
$27.54
Typical High
$47.86
Aetna
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$89.13
Typical High
$144.54
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.38
Median
$25.12
Typical High
$41.69
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$53.70
Median
$63.10
Typical High
$104.71
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.18
Median
$44.67
Typical High
$47.86
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$63.10
Median
$83.18
Typical High
$112.20
Cigna
Setting
Professional
Modifier
Global
Typical Low
$36.31
Median
$60.26
Typical High
$162.18
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.88
Median
$16.60
Typical High
$46.77
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$23.44
Median
$44.67
Typical High
$123.03
Medcost
Setting
Professional
Modifier
Global
Typical Low
$24.55
Median
$24.55
Typical High
$24.55
United
Setting
Professional
Modifier
Global
Typical Low
$48.98
Median
$74.13
Typical High
$186.21
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$18.62
Median
$30.20
Typical High
$67.61
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$31.62
Median
$53.70
Typical High
$128.82
Wellcare
Setting
Facility
Modifier
26 · Professional part
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$724.44
Median
$724.44
Typical High
$1,096.48
Wellcare
Setting
Professional
Modifier
26 · Professional part
Typical Low
$199.53
Median
$199.53
Typical High
$263.03
Wellcare
Setting
Professional
Modifier
TC · Technical part
Typical Low
$537.03
Median
$537.03
Typical High
$831.76