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Whole Exome Genetic Sequencing

Nebraska rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

How much does Whole Exome Genetic Sequencing cost?

$3,388

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $3,388 for this service. The price depends on where it is billed: about $3,162 from a physician practice, and about $4,365 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,162$3,162 to $11,482
FacilityA hospital or hospital-owned outpatient department$4,365$2,884 to $11,482

How much rates vary

Facilitymedian $4,365 · 10th to 90th $1,514 to $12,589Professionalmedian $3,162 · 10th to 90th $2,884 to $31,623
$2K$5K$10K$20Kfacility $4,365professional $3,162

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,388.44
Median
$11,481.54
Typical High
$12,589.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$3,162.28
Median
$3,162.28
Typical High
$31,622.78
BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,174.90
Median
$1,513.56
Typical High
$2,951.21
BCBS
Setting
Professional
Modifier
Global
Typical Low
$5,128.61
Median
$7,413.10
Typical High
$7,762.47
Cigna
Setting
Professional
Modifier
Global
Typical Low
$5,754.40
Median
$9,120.11
Typical High
$11,481.54
Medica
Setting
Facility
Modifier
Global
Typical Low
$2,884.03
Median
$7,244.36
Typical High
$22,908.68
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$2,884.03
Typical High
$13,803.84
Midlands
Setting
Professional
Modifier
Global
Typical Low
$9,772.37
Median
$9,772.37
Typical High
$9,772.37
United
Setting
Facility
Modifier
Global
Typical Low
$1,995.26
Median
$4,265.80
Typical High
$4,786.30
United
Setting
Professional
Modifier
Global
Typical Low
$2,754.23
Median
$2,884.03
Typical High
$13,182.57

Where Nebraska sits

The same service costs 7.2 times more in North Dakota than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 45th of 51

$3,388

ND $7,244VT $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.