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Whole Exome Genetic Sequencing

Virginia rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated October 2026.

How much does Whole Exome Genetic Sequencing cost?

$3,467

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $3,467 for this service. The price depends on where it is billed: about $3,162 from a physician practice, and about $5,888 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,162$1,995 to $3,802
FacilityA hospital or hospital-owned outpatient department$5,888$4,786 to $10,233

How much rates vary

Facilitymedian $5,888 · 10th to 90th $4,074 to $20,417Professionalmedian $3,162 · 10th to 90th $1,905 to $5,495
$2K$5K$10K$20Kfacility $5,888professional $3,162

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$3,548.13
Median
$4,073.80
Typical High
$11,220.18
Aetna
Setting
Professional
Modifier
None
Typical Low
$3,548.13
Median
$3,801.89
Typical High
$4,073.80
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$4,786.30
Median
$4,786.30
Typical High
$23,442.29
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$1,905.46
Median
$2,344.23
Typical High
$3,548.13
CareFirst
Setting
Professional
Modifier
None
Typical Low
$3,467.37
Median
$3,801.89
Typical High
$4,365.16
Cigna
Setting
Facility
Modifier
None
Typical Low
$4,897.79
Median
$7,943.28
Typical High
$12,022.64
Cigna
Setting
Professional
Modifier
None
Typical Low
$2,344.23
Median
$3,548.13
Typical High
$8,128.31
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$4,570.88
Median
$5,248.07
Typical High
$6,760.83
Medcost
Setting
Facility
Modifier
None
Typical Low
$2,511.89
Median
$4,073.80
Typical High
$6,456.54
Medcost
Setting
Professional
Modifier
None
Typical Low
$645.65
Median
$645.65
Typical High
$4,786.30
Sentara
Setting
Facility
Modifier
None
Typical Low
$3,311.31
Median
$6,456.54
Typical High
$11,481.54
Sentara
Setting
Professional
Modifier
None
Typical Low
$3,801.89
Median
$6,025.60
Typical High
$11,481.54
United
Setting
Facility
Modifier
None
Typical Low
$5,754.40
Median
$5,754.40
Typical High
$5,754.40
United
Setting
Professional
Modifier
None
Typical Low
$1,995.26
Median
$2,818.38
Typical High
$6,309.57
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,778.28
Median
$1,905.46
Typical High
$2,041.74
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$724.44
Median
$758.58
Typical High
$812.83

Where Virginia sits

The same service costs 10.7 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 36th of 51

$3,467

AK $10,715KY $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.