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Whole Exome Genetic Sequencing

North Carolina rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

How much does Whole Exome Genetic Sequencing cost?

$3,802

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $3,802 for this service. The price depends on where it is billed: about $3,802 from a physician practice, and about $4,169 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,802$3,162 to $4,786
FacilityA hospital or hospital-owned outpatient department$4,169$3,802 to $7,586

How much rates vary

Facilitymedian $4,169 · 10th to 90th $3,020 to $15,849Professionalmedian $3,802 · 10th to 90th $2,138 to $6,310
$10.0$100.0$1.0K$10.0Kfacility $4,169professional $3,802

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,019.95
Median
$4,168.69
Typical High
$15,848.93
Aetna
Setting
Professional
Modifier
Global
Typical Low
$3,019.95
Median
$3,801.89
Typical High
$5,888.44
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$2,884.03
Typical High
$2,884.03
BCBS
Setting
Facility
Modifier
Global
Typical Low
$10,715.19
Median
$14,454.40
Typical High
$14,454.40
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,137.96
Median
$4,265.80
Typical High
$7,585.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$3,801.89
Median
$10,232.93
Typical High
$21,877.62
Cigna
Setting
Professional
Modifier
Global
Typical Low
$2,187.76
Median
$2,238.72
Typical High
$6,456.54
Medcost
Setting
Professional
Modifier
Global
Typical Low
$4,570.88
Median
$4,570.88
Typical High
$4,570.88
Medcost
Setting
Facility
Modifier
Global
Typical Low
$2,511.89
Median
$3,801.89
Typical High
$6,606.93
Medcost
Setting
Professional
Modifier
Global
Typical Low
$645.65
Median
$645.65
Typical High
$4,570.88
United
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$4,786.30
Typical High
$5,754.40
United
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$2,398.83
Typical High
$4,786.30
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$22,908.68
Median
$22,908.68
Typical High
$22,908.68
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$23,988.33
Median
$23,988.33
Typical High
$35,481.34

Where North Carolina sits

The same service costs 7.2 times more in North Dakota than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

North Carolina $3,802 · 31st of 51
ND $7,244VT $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.