go back

Whole Exome Genetic Sequencing

Illinois rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

How much does Whole Exome Genetic Sequencing cost?

$3,890

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $3,890 for this service. The price depends on where it is billed: about $3,715 from a physician practice, and about $7,413 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,715$1,000 to $4,074
FacilityA hospital or hospital-owned outpatient department$7,413$4,898 to $9,772

How much rates vary

Facilitymedian $7,413 · 10th to 90th $3,890 to $13,183Professionalmedian $3,715 · 10th to 90th $3 to $7,586
$10.0$100.0$1.0K$10.0Kfacility $7,413professional $3,715

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,890.45
Median
$7,413.10
Typical High
$9,772.37
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,000.00
Median
$3,890.45
Typical High
$8,912.51
BCBS
Setting
Facility
Modifier
Global
Typical Low
$5,888.44
Median
$16,595.87
Typical High
$60,255.96
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$3,311.31
Typical High
$3,715.35
Cigna
Setting
Facility
Modifier
Global
Typical Low
$6,165.95
Median
$10,964.78
Typical High
$21,877.62
Cigna
Setting
Professional
Modifier
Global
Typical Low
$2,344.23
Median
$5,495.41
Typical High
$8,128.31
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$3,801.89
Median
$8,317.64
Typical High
$16,595.87
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$6,165.95
Median
$6,165.95
Typical High
$6,165.95
Molina
Setting
Professional
Modifier
Global
Typical Low
$2,630.27
Median
$2,630.27
Typical High
$6,025.60
United
Setting
Facility
Modifier
Global
Typical Low
$3,235.94
Median
$4,786.30
Typical High
$9,549.93
United
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$2,884.03
Typical High
$4,786.30

Where Illinois sits

The same service costs 7.2 times more in North Dakota than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Illinois $3,890 · 26th of 51
ND $7,244VT $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.