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Whole Exome Genetic Sequencing

Indiana rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated October 2026.

How much does Whole Exome Genetic Sequencing cost?

$3,311

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $3,311 for this service. The price depends on where it is billed: about $2,884 from a physician practice, and about $4,786 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,884$1,905 to $4,074
FacilityA hospital or hospital-owned outpatient department$4,786$4,266 to $9,550

How much rates vary

Facilitymedian $4,786 · 10th to 90th $3,802 to $14,454Professionalmedian $2,884 · 10th to 90th $1,905 to $5,888
$100$500$2K$10Kfacility $4,786professional $2,884

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$3,890.45
Median
$7,244.36
Typical High
$17,782.79
Aetna
Setting
Professional
Modifier
None
Typical Low
$3,548.13
Median
$3,890.45
Typical High
$7,244.36
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$3,801.89
Median
$4,786.30
Typical High
$14,454.40
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$1,905.46
Median
$1,905.46
Typical High
$5,248.07
CareSource
Setting
Facility
Modifier
None
Typical Low
$6,025.60
Median
$6,025.60
Typical High
$6,025.60
Cigna
Setting
Facility
Modifier
None
Typical Low
$3,090.30
Median
$4,786.30
Typical High
$13,489.63
Cigna
Setting
Professional
Modifier
None
Typical Low
$2,290.87
Median
$4,265.80
Typical High
$9,120.11
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$912.01
Median
$7,943.28
Typical High
$14,454.40
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None
Typical Low
$3,467.37
Median
$4,073.80
Typical High
$7,244.36
United
Setting
Professional
Modifier
None
Typical Low
$1,995.26
Median
$2,884.03
Typical High
$5,754.40
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,778.28
Median
$1,949.84
Typical High
$3,548.13
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$724.44
Median
$776.25
Typical High
$1,445.44

Where Indiana sits

The same service costs 10.7 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 37th of 51

$3,311

AK $10,715KY $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.