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Whole Exome Genetic Sequencing

Indiana rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

How much does Whole Exome Genetic Sequencing cost?

$3,890

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $3,890 for this service. The price depends on where it is billed: about $3,890 from a physician practice, and about $4,786 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,890$1,905 to $3,890
FacilityA hospital or hospital-owned outpatient department$4,786$4,786 to $9,550

How much rates vary

Facilitymedian $4,786 · 10th to 90th $4,365 to $14,454Professionalmedian $3,890 · 10th to 90th $1,000 to $4,169
$10.0$100.0$1.0K$10.0Kfacility $4,786professional $3,890

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,890.45
Median
$5,248.07
Typical High
$14,454.40
Aetna
Setting
Professional
Modifier
Global
Typical Low
$3,019.95
Median
$3,890.45
Typical High
$4,168.69
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$4,786.30
Median
$4,786.30
Typical High
$14,454.40
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$1,905.46
Typical High
$3,630.78
CareSource
Setting
Facility
Modifier
Global
Typical Low
$6,025.60
Median
$6,025.60
Typical High
$6,025.60
Cigna
Setting
Facility
Modifier
Global
Typical Low
$3,467.37
Median
$4,786.30
Typical High
$9,120.11
Cigna
Setting
Professional
Modifier
Global
Typical Low
$2,187.76
Median
$4,265.80
Typical High
$6,918.31
United
Setting
Facility
Modifier
Global
Typical Low
$2,630.27
Median
$4,786.30
Typical High
$4,786.30
United
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$2,884.03
Typical High
$5,248.07

Where Indiana sits

The same service costs 7.2 times more in North Dakota than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Indiana $3,890 · 28th of 51
ND $7,244VT $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.