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Whole Exome Genetic Sequencing

Massachusetts rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

Facilitymedian $6,607 · 10th–90th $2,884$15,4880%10%10th90th$6,607Professionalmedian $4,786 · 10th–90th $1,000$10,9650%20%40%10th90th$4,786$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$1,000.00
Median
$8,317.64
Typical High
$14,125.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,000.00
Median
$1,000.00
Typical High
$14,454.40
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$3,548.13
Median
$5,495.41
Typical High
$22,908.68
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$4,786.30
Typical High
$14,125.38
BCBS
Setting
Professional
Modifier
Global
Typical Low
$4,365.16
Median
$4,365.16
Typical High
$4,677.35
Cigna
Setting
Facility
Modifier
Global
Typical Low
$3,162.28
Median
$3,801.89
Typical High
$7,762.47
Cigna
Setting
Professional
Modifier
Global
Typical Low
$2,398.83
Median
$4,570.88
Typical High
$10,000.00
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$5,888.44
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$3,548.13
Median
$6,918.31
Typical High
$8,128.31
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$4,786.30
Median
$4,786.30
Typical High
$7,943.28
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$3,548.13
Median
$5,495.41
Typical High
$22,908.68
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$4,786.30
Typical High
$14,125.38
United
Setting
Facility
Modifier
Global
Typical Low
$2,630.27
Median
$4,786.30
Typical High
$5,754.40
United
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$4,786.30
Typical High
$8,511.38