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Whole Exome Genetic Sequencing

New York rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

How much does Whole Exome Genetic Sequencing cost?

$4,074

Typical negotiated rate. In New York, July 2026.

Insurers have agreed to pay about $4,074 for this service. The price depends on where it is billed: about $2,884 from a physician practice, and about $8,128 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,884$1,905 to $4,786
FacilityA hospital or hospital-owned outpatient department$8,128$4,898 to $10,965

How much rates vary

Facilitymedian $8,128 · 10th to 90th $4,074 to $13,183Professionalmedian $2,884 · 10th to 90th $1,000 to $7,244
$100.0$1.0K$10.0K$100.0Kfacility $8,128professional $2,884

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$4,073.80
Median
$8,128.31
Typical High
$13,182.57
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,000.00
Median
$3,235.94
Typical High
$7,244.36
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$4,786.30
Median
$4,786.30
Typical High
$12,302.69
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$1,905.46
Typical High
$6,918.31
CDPHP
Setting
Facility
Modifier
Global
Typical Low
$2,884.03
Median
$4,786.30
Typical High
$4,786.30
CDPHP
Setting
Professional
Modifier
Global
Typical Low
$4,786.30
Median
$4,786.30
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$4,677.35
Median
$10,232.93
Typical High
$12,302.69
Cigna
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$6,456.54
Typical High
$22,908.68
Emblem Health
Setting
Facility
Modifier
Global
Typical Low
$4,786.30
Median
$7,943.28
Typical High
$18,197.01
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$2,398.83
Median
$3,311.31
Typical High
$8,511.38
Excellus BCBS
Setting
Professional
Modifier
Global
Typical Low
$3,162.28
Median
$4,570.88
Typical High
$8,511.38
MVP Health Care
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$6,165.95
Typical High
$50,118.72
MVP Health Care
Setting
Professional
Modifier
Global
Typical Low
$645.65
Median
$4,786.30
Typical High
$8,317.64
United
Setting
Facility
Modifier
Global
Typical Low
$3,090.30
Median
$4,786.30
Typical High
$6,025.60
United
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$3,311.31
Typical High
$7,244.36
Univera
Setting
Facility
Modifier
Global
Typical Low
$4,073.80
Median
$5,011.87
Typical High
$5,011.87
Univera
Setting
Professional
Modifier
Global
Typical Low
$3,235.94
Median
$4,570.88
Typical High
$11,481.54

Where New York sits

The same service costs 7.2 times more in North Dakota than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

New York $4,074 · 24th of 51
ND $7,244VT $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.