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Whole Exome Genetic Sequencing

New York rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated October 2026.

How much does Whole Exome Genetic Sequencing cost?

$3,311

Typical negotiated rate. In New York, October 2026.

Insurers have agreed to pay about $3,311 for this service. The price depends on where it is billed: about $3,090 from a physician practice, and about $8,318 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,090$1,905 to $5,012
FacilityA hospital or hospital-owned outpatient department$8,318$4,786 to $11,749

How much rates vary

Facilitymedian $8,318 · 10th to 90th $3,090 to $12,303Professionalmedian $3,090 · 10th to 90th $1,000 to $8,318
$100$1K$10Kfacility $8,318professional $3,090

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$1,000.00
Median
$4,073.80
Typical High
$14,791.08
Aetna
Setting
Professional
Modifier
None
Typical Low
$1,000.00
Median
$1,000.00
Typical High
$4,073.80
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$4,786.30
Median
$4,786.30
Typical High
$12,302.69
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$1,905.46
Median
$3,311.31
Typical High
$9,549.93
CDPHP
Setting
Professional
Modifier
None
Typical Low
$4,786.30
Median
$4,786.30
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
None
Typical Low
$4,677.35
Median
$10,232.93
Typical High
$13,803.84
Cigna
Setting
Professional
Modifier
None
Typical Low
$2,884.03
Median
$5,754.40
Typical High
$22,908.68
Emblem Health
Setting
Facility
Modifier
None
Typical Low
$4,786.30
Median
$7,943.28
Typical High
$13,182.57
Emblem Health
Setting
Professional
Modifier
None
Typical Low
$2,818.38
Median
$3,311.31
Typical High
$6,918.31
Excellus BCBS
Setting
Professional
Modifier
None
Typical Low
$3,090.30
Median
$4,786.30
Typical High
$5,495.41
MVP Health Care
Setting
Facility
Modifier
None
Typical Low
$13.80
Median
$257.04
Typical High
$9,549.93
MVP Health Care
Setting
Professional
Modifier
None
Typical Low
$645.65
Median
$645.65
Typical High
$9,772.37
United
Setting
Facility
Modifier
None
Typical Low
$4,265.80
Median
$4,786.30
Typical High
$6,025.60
United
Setting
Professional
Modifier
None
Typical Low
$1,995.26
Median
$2,344.23
Typical High
$7,244.36
Univera
Setting
Facility
Modifier
None
Typical Low
$3,090.30
Median
$3,090.30
Typical High
$5,011.87
Univera
Setting
Professional
Modifier
None
Typical Low
$3,090.30
Median
$4,570.88
Typical High
$5,495.41
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$501.19
Median
$501.19
Typical High
$2,041.74
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$199.53
Median
$199.53
Typical High
$812.83

Where New York sits

The same service costs 10.7 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New York· 39th of 51

$3,311

AK $10,715KY $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.