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Whole Exome Genetic Sequencing

Florida rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

How much does Whole Exome Genetic Sequencing cost?

$3,311

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $3,311 for this service. The price depends on where it is billed: about $3,162 from a physician practice, and about $6,607 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,162$1,000 to $3,467
FacilityA hospital or hospital-owned outpatient department$6,607$4,074 to $13,804

How much rates vary

Facilitymedian $6,607 · 10th to 90th $2,884 to $23,442Professionalmedian $3,162 · 10th to 90th $1,000 to $4,169
$100$1K$10Kfacility $6,607professional $3,162

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,467.37
Median
$6,165.95
Typical High
$25,703.96
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,000.00
Median
$3,235.94
Typical High
$3,890.45
AvMed
Setting
Facility
Modifier
Global
Typical Low
$4,265.80
Median
$4,786.30
Typical High
$5,623.41
AvMed
Setting
Professional
Modifier
Global
Typical Low
$14.13
Median
$4,786.30
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,754.23
Median
$3,981.07
Typical High
$13,803.84
Cigna
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$3,890.45
Typical High
$8,317.64
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$8,912.51
Median
$8,912.51
Typical High
$8,912.51
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$2,884.03
Typical High
$4,786.30
Molina
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$3,162.28
Typical High
$4,786.30
United
Setting
Facility
Modifier
Global
Typical Low
$1,995.26
Median
$4,265.80
Typical High
$4,786.30
United
Setting
Professional
Modifier
Global
Typical Low
$1,659.59
Median
$1,995.26
Typical High
$6,025.60
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$2,884.03
Typical High
$4,786.30

Where Florida sits

The same service costs 7.2 times more in North Dakota than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 46th of 51

$3,311

ND $7,244VT $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.