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Whole Exome Genetic Sequencing

Florida rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated October 2026.

How much does Whole Exome Genetic Sequencing cost?

$2,884

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $2,884 for this service. The price depends on where it is billed: about $2,884 from a physician practice, and about $8,913 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,884$1,995 to $3,802
FacilityA hospital or hospital-owned outpatient department$8,913$4,786 to $8,913

How much rates vary

Facilitymedian $8,913 · 10th to 90th $3,631 to $8,913Professionalmedian $2,884 · 10th to 90th $1,000 to $5,754
$100$1K$10Kfacility $8,913professional $2,884

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$1,000.00
Typical High
$3,548.13
Aetna
Setting
Professional
Modifier
None
Typical Low
$1,000.00
Median
$1,000.00
Typical High
$3,890.45
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$501.19
Median
$501.19
Typical High
$1,949.84
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$199.53
Median
$199.53
Typical High
$776.25
AvMed
Setting
Facility
Modifier
None
Typical Low
$3,801.89
Median
$4,786.30
Typical High
$5,888.44
AvMed
Setting
Professional
Modifier
None
Typical Low
$3,801.89
Median
$4,786.30
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
None
Typical Low
$2,754.23
Median
$4,073.80
Typical High
$19,498.45
Cigna
Setting
Professional
Modifier
None
Typical Low
$2,238.72
Median
$3,801.89
Typical High
$8,317.64
Florida Blue
Setting
Facility
Modifier
None
Typical Low
$8,912.51
Median
$8,912.51
Typical High
$8,912.51
Florida Blue
Setting
Professional
Modifier
None
Typical Low
$2,884.03
Median
$3,801.89
Typical High
$6,025.60
Molina
Setting
Professional
Modifier
None
Typical Low
$2,884.03
Median
$3,162.28
Typical High
$3,890.45
United
Setting
Facility
Modifier
None
Typical Low
$4,786.30
Median
$4,786.30
Typical High
$4,786.30
United
Setting
Professional
Modifier
None
Typical Low
$1,659.59
Median
$1,995.26
Typical High
$6,025.60
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$2,884.03
Median
$2,884.03
Typical High
$4,786.30

Where Florida sits

The same service costs 10.7 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 47th of 51

$2,884

AK $10,715KY $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.