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Whole Exome Genetic Sequencing

Minnesota rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated October 2026.

How much does Whole Exome Genetic Sequencing cost?

$4,786

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $4,786 for this service. The price depends on where it is billed: about $4,786 from a physician practice, and about $4,786 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$4,786$4,266 to $5,754
FacilityA hospital or hospital-owned outpatient department$4,786$4,467 to $11,220

How much rates vary

Facilitymedian $4,786 · 10th to 90th $871 to $19,055Professionalmedian $4,786 · 10th to 90th $2,884 to $9,550
$200$1K$5K$20Kfacility $4,786professional $4,786

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$4,466.84
Median
$4,466.84
Typical High
$4,466.84
Aetna
Setting
Professional
Modifier
None
Typical Low
$4,073.80
Median
$4,466.84
Typical High
$5,754.40
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$229.09
Median
$4,570.88
Typical High
$4,786.30
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$3,801.89
Median
$4,265.80
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
None
Typical Low
$5,754.40
Median
$15,135.61
Typical High
$44,668.36
Cigna
Setting
Professional
Modifier
None
Typical Low
$5,495.41
Median
$6,309.57
Typical High
$9,332.54
Health Partners
Setting
Facility
Modifier
None
Typical Low
$8,912.51
Median
$14,791.08
Typical High
$35,481.34
Health Partners
Setting
Professional
Modifier
None
Typical Low
$5,495.41
Median
$5,495.41
Typical High
$9,120.11
Medica
Setting
Facility
Modifier
None
Typical Low
$4,786.30
Median
$7,585.78
Typical High
$22,908.68
Medica
Setting
Professional
Modifier
None
Typical Low
$2,454.71
Median
$4,786.30
Typical High
$23,988.33
United
Setting
Facility
Modifier
None
Typical Low
$4,786.30
Median
$4,786.30
Typical High
$5,754.40
United
Setting
Professional
Modifier
None
Typical Low
$1,995.26
Median
$4,265.80
Typical High
$10,715.19
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$2,238.72
Median
$2,238.72
Typical High
$2,238.72
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$891.25
Median
$891.25
Typical High
$891.25
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$2,238.72
Median
$2,238.72
Typical High
$2,884.03
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$891.25
Median
$891.25
Typical High
$1,148.15

Where Minnesota sits

The same service costs 10.7 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 18th of 51

$4,786

AK $10,715KY $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.