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Whole Exome Genetic Sequencing

Minnesota rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

How much does Whole Exome Genetic Sequencing cost?

$4,786

Typical negotiated rate. In Minnesota, July 2026.

Insurers have agreed to pay about $4,786 for this service. The price depends on where it is billed: about $4,786 from a physician practice, and about $10,715 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$4,786$4,467 to $5,495
FacilityA hospital or hospital-owned outpatient department$10,715$4,786 to $17,783

How much rates vary

Facilitymedian $10,715 · 10th to 90th $3,548 to $35,481Professionalmedian $4,786 · 10th to 90th $3,802 to $6,918
$10.0$100.0$1.0K$10.0Kfacility $10,715professional $4,786

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$4,466.84
Median
$4,466.84
Typical High
$4,466.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$3,019.95
Median
$3,715.35
Typical High
$6,606.93
BCBS
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$4,786.30
Typical High
$4,786.30
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3,801.89
Median
$4,786.30
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$9,332.54
Median
$16,218.10
Typical High
$44,668.36
Cigna
Setting
Professional
Modifier
Global
Typical Low
$5,495.41
Median
$6,918.31
Typical High
$9,772.37
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$10,471.29
Median
$15,135.61
Typical High
$35,481.34
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$5,495.41
Median
$5,495.41
Typical High
$9,120.11
Medica
Setting
Facility
Modifier
Global
Typical Low
$4,265.80
Median
$8,317.64
Typical High
$15,135.61
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$2,884.03
Typical High
$10,964.78
United
Setting
Facility
Modifier
Global
Typical Low
$2,754.23
Median
$4,786.30
Typical High
$5,754.40
United
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$4,786.30
Typical High
$10,471.29

Where Minnesota sits

The same service costs 7.2 times more in North Dakota than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Minnesota $4,786 · 17th of 51
ND $7,244VT $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.