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Whole Exome Genetic Sequencing

Missouri rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

How much does Whole Exome Genetic Sequencing cost?

$4,786

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $4,786 for this service. The price depends on where it is billed: about $4,266 from a physician practice, and about $6,310 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$4,266$2,884 to $5,754
FacilityA hospital or hospital-owned outpatient department$6,310$4,786 to $8,318

How much rates vary

Facilitymedian $6,310 · 10th to 90th $3,981 to $10,965Professionalmedian $4,266 · 10th to 90th $1,905 to $9,772
$1K$2K$5K$10K$20Kfacility $6,310professional $4,266

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,981.07
Median
$7,943.28
Typical High
$10,000.00
Aetna
Setting
Professional
Modifier
Global
Typical Low
$4,073.80
Median
$5,011.87
Typical High
$10,232.93
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$4,786.30
Median
$4,786.30
Typical High
$16,595.87
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$851.14
Median
$2,951.21
Typical High
$8,511.38
BCBS
Setting
Facility
Modifier
Global
Typical Low
$6,606.93
Median
$7,079.46
Typical High
$12,302.69
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3,311.31
Median
$4,786.30
Typical High
$5,370.32
Cigna
Setting
Facility
Modifier
Global
Typical Low
$4,897.79
Median
$8,912.51
Typical High
$12,882.50
Cigna
Setting
Professional
Modifier
Global
Typical Low
$2,187.76
Median
$4,073.80
Typical High
$6,918.31
Medica
Setting
Facility
Modifier
Global
Typical Low
$3,890.45
Median
$6,025.60
Typical High
$22,908.68
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$2,884.03
Typical High
$23,988.33
United
Setting
Facility
Modifier
Global
Typical Low
$2,137.96
Median
$4,786.30
Typical High
$5,754.40
United
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$2,884.03
Typical High
$6,456.54

Where Missouri sits

The same service costs 7.2 times more in North Dakota than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 16th of 51

$4,786

ND $7,244VT $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.