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Whole Exome Genetic Sequencing

Michigan rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated October 2026.

How much does Whole Exome Genetic Sequencing cost?

$4,467

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $4,467 for this service. The price depends on where it is billed: about $4,467 from a physician practice, and about $4,571 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$4,467$3,548 to $4,786
FacilityA hospital or hospital-owned outpatient department$4,571$4,571 to $6,310

How much rates vary

Facilitymedian $4,571 · 10th to 90th $3,548 to $8,913Professionalmedian $4,467 · 10th to 90th $2,884 to $5,495
$10$100$1K$10Kfacility $4,571professional $4,467

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$4,570.88
Median
$4,570.88
Typical High
$7,079.46
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$3,548.13
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$912.01
Median
$912.01
Typical High
$1,412.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$4,073.80
Median
$4,677.35
Typical High
$4,786.30
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$2,041.74
Median
$2,344.23
Typical High
$2,398.83
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$812.83
Median
$933.25
Typical High
$954.99
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$3,548.13
Median
$5,370.32
Typical High
$9,120.11
BCBS Michigan
Setting
Professional
Modifier
None
Typical Low
$3,388.44
Median
$3,548.13
Typical High
$3,548.13
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,995.26
Median
$4,786.30
Typical High
$6,918.31
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$4,570.88
Median
$4,570.88
Typical High
$12,022.64
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$3,548.13
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$912.01
Median
$912.01
Typical High
$1,412.54
Health Alliance Plan
Setting
Professional
Modifier
None
Typical Low
$4,466.84
Median
$4,570.88
Typical High
$6,025.60
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$2,290.87
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$912.01
Median
$912.01
Typical High
$912.01
Priority Health
Setting
Professional
Modifier
None
Typical Low
$1,995.26
Median
$4,786.30
Typical High
$6,606.93
United
Setting
Facility
Modifier
None
Typical Low
$2,884.03
Median
$4,265.80
Typical High
$5,754.40
United
Setting
Professional
Modifier
None
Typical Low
$1,995.26
Median
$2,884.03
Typical High
$4,786.30

Where Michigan sits

The same service costs 10.7 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 22nd of 51

$4,467

AK $10,715KY $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.