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Whole Exome Genetic Sequencing

Colorado rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

How much does Whole Exome Genetic Sequencing cost?

$4,074

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $4,074 for this service. The price depends on where it is billed: about $3,631 from a physician practice, and about $10,471 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,631$2,884 to $4,074
FacilityA hospital or hospital-owned outpatient department$10,471$5,623 to $19,498

How much rates vary

Facilitymedian $10,471 · 10th to 90th $3,631 to $22,909Professionalmedian $3,631 · 10th to 90th $1,905 to $4,571
$1K$2K$5K$10K$20Kfacility $10,471professional $3,631

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,019.95
Median
$5,888.44
Typical High
$21,877.62
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,511.89
Median
$3,715.35
Typical High
$4,466.84
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$6,025.60
Median
$14,125.38
Typical High
$23,988.33
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$1,995.26
Typical High
$3,630.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,570.40
Median
$3,090.30
Typical High
$12,589.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$2,238.72
Median
$2,570.40
Typical High
$6,918.31
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$3,467.37
Median
$4,786.30
Typical High
$7,244.36
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$6,760.83
Median
$6,760.83
Typical High
$15,488.17
Select Health
Setting
Facility
Modifier
Global
Typical Low
$5,011.87
Median
$8,912.51
Typical High
$10,000.00
Select Health
Setting
Professional
Modifier
Global
Typical Low
$3,311.31
Median
$4,786.30
Typical High
$7,244.36
United
Setting
Facility
Modifier
Global
Typical Low
$2,884.03
Median
$4,786.30
Typical High
$7,244.36
United
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$1,995.26
Typical High
$3,548.13

Where Colorado sits

The same service costs 7.2 times more in North Dakota than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 23rd of 51

$4,074

ND $7,244VT $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.