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Whole Exome Genetic Sequencing

Nationwide rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated July 2026.

Facilitymedian $6,166 · 10th–90th $3,020$19,0550%20%10th90th$6,166Professionalmedian $3,802 · 10th–90th $1,000$7,5860%20%10th90th$3,802$0.0$0.5$10.0$200.0$5.0K$100.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,311.31
Median
$6,606.93
Typical High
$16,595.87
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,000.00
Median
$3,715.35
Typical High
$6,918.31
BCBS
Setting
Facility
Modifier
Global
Typical Low
$4,073.80
Median
$6,456.54
Typical High
$20,417.38
BCBS
Setting
Professional
Modifier
Global
Typical Low
$794.33
Median
$1,905.46
Typical High
$6,165.95
Cigna
Setting
Facility
Modifier
Global
Typical Low
$3,311.31
Median
$9,120.11
Typical High
$20,417.38
Cigna
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$5,495.41
Typical High
$11,481.54
United
Setting
Facility
Modifier
Global
Typical Low
$1,995.26
Median
$4,786.30
Typical High
$5,754.40
United
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$2,884.03
Typical High
$6,456.54