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Whole Exome Genetic Sequencing

Kentucky rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated October 2026.

How much does Whole Exome Genetic Sequencing cost?

$1,000

Typical negotiated rate. In Kentucky, October 2026.

Insurers have agreed to pay about $1,000 for this service. The price depends on where it is billed: about $794 from a physician practice, and about $4,266 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$794$603 to $2,884
FacilityA hospital or hospital-owned outpatient department$4,266$3,890 to $6,918

How much rates vary

Facilitymedian $4,266 · 10th to 90th $2,951 to $6,918Professionalmedian $794 · 10th to 90th $100 to $5,754
$100$500$2K$10Kfacility $4,266professional $794

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$1,000.00
Median
$3,890.45
Typical High
$3,981.07
Aetna
Setting
Professional
Modifier
None
Typical Low
$1,000.00
Median
$3,890.45
Typical High
$4,786.30
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$2,951.21
Median
$4,786.30
Typical High
$5,011.87
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$100.00
Median
$794.33
Typical High
$1,905.46
CareSource
Setting
Facility
Modifier
None
Typical Low
$4,786.30
Median
$5,754.40
Typical High
$6,760.83
CareSource
Setting
Professional
Modifier
None
Typical Low
$5,128.61
Median
$6,165.95
Typical High
$7,943.28
Cigna
Setting
Facility
Modifier
None
Typical Low
$3,715.35
Median
$6,918.31
Typical High
$10,232.93
Cigna
Setting
Professional
Modifier
None
Typical Low
$2,398.83
Median
$22,908.68
Typical High
$22,908.68
United
Setting
Professional
Modifier
None
Typical Low
$1,995.26
Median
$2,884.03
Typical High
$5,248.07
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$501.19
Median
$1,949.84
Typical High
$2,398.83
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$199.53
Median
$776.25
Typical High
$954.99

Where Kentucky sits

The same service costs 10.7 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 51st of 51

$1,000

AK $10,715KY $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.