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Whole Exome Genetic Sequencing

Mississippi rates for HCPCS 81415

Reads the protein-coding portions of essentially all of a person's genes from a blood or saliva sample, searching for a change that explains a condition present from birth or running in the family that has no clear cause. It is used when the features do not point to one suspected gene, so a broad search is more likely to find an answer than testing genes one at a time. A result may identify a cause, be inconclusive, or turn up a change whose meaning is not yet known.

Rates data updated October 2026.

How much does Whole Exome Genetic Sequencing cost?

$5,888

Typical negotiated rate. In Mississippi, October 2026.

Insurers have agreed to pay about $5,888 for this service. The price depends on where it is billed: about $5,129 from a physician practice, and about $5,888 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$5,129$2,630 to $5,888
FacilityA hospital or hospital-owned outpatient department$5,888$5,888 to $5,888

How much rates vary

Facilitymedian $5,888 · 10th to 90th $4,266 to $8,511Professionalmedian $5,129 · 10th to 90th $2,188 to $8,511
$2K$5K$10Kfacility $5,888professional $5,129

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$5,128.61
Median
$8,511.38
Typical High
$9,772.37
Aetna
Setting
Professional
Modifier
None
Typical Low
$3,801.89
Median
$8,511.38
Typical High
$9,772.37
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,905.46
Median
$4,265.80
Typical High
$4,897.79
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$758.58
Median
$1,737.80
Typical High
$1,949.84
BCBS Mississippi
Setting
Facility
Modifier
None
Typical Low
$5,888.44
Median
$5,888.44
Typical High
$5,888.44
BCBS Mississippi
Setting
Professional
Modifier
None
Typical Low
$5,888.44
Median
$5,888.44
Typical High
$5,888.44
Cigna
Setting
Facility
Modifier
None
Typical Low
$3,090.30
Median
$3,235.94
Typical High
$3,981.07
Cigna
Setting
Professional
Modifier
None
Typical Low
$2,089.30
Median
$2,187.76
Typical High
$5,754.40
United
Setting
Facility
Modifier
None
Typical Low
$4,265.80
Median
$4,265.80
Typical High
$5,754.40
United
Setting
Professional
Modifier
None
Typical Low
$1,995.26
Median
$2,630.27
Typical High
$10,715.19

Where Mississippi sits

The same service costs 10.7 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Mississippi· 6th of 51

$5,888

AK $10,715KY $1,000

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.