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Mitochondrial DNA Large Deletion Test

South Dakota rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated July 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$1,413

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $1,413 for this service. The price depends on where it is billed: about $1,122 from a physician practice, and about $1,778 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$1,122$724 to $2,188
FacilityA hospital or hospital-owned outpatient department$1,778$1,479 to $1,778

How much rates vary

Facilitymedian $1,778 · 10th to 90th $891 to $1,778Professionalmedian $1,122 · 10th to 90th $631 to $2,239
$0.1$1.0$10.0$100.0$1.0Kfacility $1,778professional $1,122

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$660.69
Median
$1,071.52
Typical High
$1,071.52
Aetna
Setting
Professional
Modifier
Global
Typical Low
$630.96
Median
$724.44
Typical High
$870.96
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,778.28
Median
$1,778.28
Typical High
$1,778.28
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,318.26
Median
$1,778.28
Typical High
$2,238.72
Medica
Setting
Facility
Modifier
Global
Typical Low
$0.02
Median
$1,071.52
Typical High
$4,466.84
Medica
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$478.63
Typical High
$4,677.35
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$2,187.76
Typical High
$2,570.40
United
Setting
Facility
Modifier
Global
Typical Low
$1,122.02
Median
$1,122.02
Typical High
$1,122.02
United
Setting
Professional
Modifier
Global
Typical Low
$389.05
Median
$562.34
Typical High
$1,230.27
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$933.25
Median
$933.25
Typical High
$933.25

Where South Dakota sits

The same service costs 2.0 times more in South Dakota than in Washington, DC. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Dakota $1,413 · 1st of 51
SD $1,413DC $708

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.