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Mitochondrial DNA Large Deletion Test

South Dakota rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$1,072

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $1,072 for this service. The price depends on where it is billed: about $933 from a physician practice, and about $1,072 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$933$724 to $1,778
FacilityA hospital or hospital-owned outpatient department$1,072$1,072 to $1,778

How much rates vary

Facilitymedian $1,072 · 10th to 90th $891 to $1,778Professionalmedian $933 · 10th to 90th $479 to $2,239
$500$1K$2K$5Kfacility $1,072professional $933

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$660.69
Median
$660.69
Typical High
$1,071.52
Aetna
Setting
Professional
Modifier
None
Typical Low
$630.96
Median
$630.96
Typical High
$870.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,778.28
Median
$1,778.28
Typical High
$1,778.28
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,071.52
Median
$1,778.28
Typical High
$2,238.72
Medica
Setting
Facility
Modifier
None
Typical Low
$891.25
Median
$1,071.52
Typical High
$1,737.80
Medica
Setting
Professional
Modifier
None
Typical Low
$478.63
Median
$851.14
Typical High
$1,698.24
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$1,412.54
Median
$2,187.76
Typical High
$2,570.40
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$562.34
Typical High
$933.25
Wellmark
Setting
Professional
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$933.25

Where South Dakota sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 11th of 51

$1,072

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.