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Mitochondrial DNA Large Deletion Test

Massachusetts rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated July 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$933

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $933 for this service. The price depends on where it is billed: about $933 from a physician practice, and about $1,862 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$933$933 to $1,148
FacilityA hospital or hospital-owned outpatient department$1,862$1,148 to $2,692

How much rates vary

Facilitymedian $1,862 · 10th to 90th $851 to $3,020Professionalmedian $933 · 10th to 90th $617 to $2,188
$100.0$1.0K$10.0Kfacility $1,862professional $933

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$933.25
Median
$1,778.28
Typical High
$2,754.23
Aetna
Setting
Professional
Modifier
Global
Typical Low
$870.96
Median
$1,148.15
Typical High
$2,818.38
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$691.83
Median
$1,071.52
Typical High
$4,466.84
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$562.34
Median
$933.25
Typical High
$2,754.23
BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,479.11
Median
$1,862.09
Typical High
$2,691.53
BCBS
Setting
Professional
Modifier
Global
Typical Low
$870.96
Median
$870.96
Typical High
$870.96
Cigna
Setting
Facility
Modifier
Global
Typical Low
$616.60
Median
$741.31
Typical High
$1,513.56
Cigna
Setting
Professional
Modifier
Global
Typical Low
$467.74
Median
$891.25
Typical High
$1,949.84
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$707.95
Median
$1,348.96
Typical High
$1,584.89
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$933.25
Median
$933.25
Typical High
$1,548.82
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$691.83
Median
$1,071.52
Typical High
$4,466.84
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$562.34
Median
$933.25
Typical High
$2,754.23
United
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$933.25
Typical High
$1,122.02
United
Setting
Professional
Modifier
Global
Typical Low
$562.34
Median
$933.25
Typical High
$1,778.28

Where Massachusetts sits

The same service costs 2.0 times more in South Dakota than in Washington, DC. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Massachusetts $933 · 22nd of 51
SD $1,413DC $708

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.