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Mitochondrial DNA Large Deletion Test

North Carolina rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$794

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $794 for this service. The price depends on where it is billed: about $794 from a physician practice, and about $933 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$794$562 to $1,096
FacilityA hospital or hospital-owned outpatient department$933$741 to $2,630

How much rates vary

Facilitymedian $933 · 10th to 90th $708 to $4,266Professionalmedian $794 · 10th to 90th $417 to $1,413
$500$1K$2K$5Kfacility $933professional $794

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$741.31
Median
$741.31
Typical High
$1,548.82
Aetna
Setting
Professional
Modifier
None
Typical Low
$724.44
Median
$741.31
Typical High
$891.25
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$2,089.30
Median
$2,818.38
Typical High
$2,818.38
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$416.87
Median
$933.25
Typical High
$1,513.56
Cigna
Setting
Facility
Modifier
None
Typical Low
$776.25
Median
$2,454.71
Typical High
$4,265.80
Cigna
Setting
Professional
Modifier
None
Typical Low
$436.52
Median
$524.81
Typical High
$1,348.96
Medcost
Setting
Professional
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$933.25
Medcost
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$741.31
Typical High
$977.24
Medcost
Setting
Professional
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$1,621.81
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$467.74
Typical High
$933.25
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$371.54
Median
$371.54
Typical High
$467.74
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$151.36
Median
$151.36
Typical High
$186.21
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$467.74
Median
$467.74
Typical High
$1,288.25

Where North Carolina sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 31st of 51

$794

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.