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Mitochondrial DNA Large Deletion Test

Maine rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$741

Typical negotiated rate. In Maine, October 2026.

Insurers have agreed to pay about $741 for this service. Most negotiated rates run $479 to $1,047.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $1,148 · 10th to 90th $912 to $1,479Professionalmedian $562 · 10th to 90th $372 to $1,349
$500$1K$2K$5Kfacility $1,148professional $562

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$758.58
Median
$758.58
Typical High
$1,148.15
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$912.01
Median
$1,148.15
Typical High
$1,380.38
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$457.09
Typical High
$602.56
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,479.11
Median
$1,479.11
Typical High
$2,137.96
Cigna
Setting
Professional
Modifier
None
Typical Low
$851.14
Median
$954.99
Typical High
$1,071.52
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$562.34
Median
$933.25
Typical High
$1,621.81
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$758.58
Median
$758.58
Typical High
$758.58
United
Setting
Professional
Modifier
None
Typical Low
$562.34
Median
$562.34
Typical High
$1,621.81
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$380.19
Median
$380.19
Typical High
$575.44
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$151.36
Median
$151.36
Typical High
$229.09

Where Maine sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 35th of 51

$741

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.