go back

Mitochondrial DNA Large Deletion Test

Maryland rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$692

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $692 for this service. Most negotiated rates run $603 to $741.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $617 · 10th to 90th $501 to $1,202Professionalmedian $708 · 10th to 90th $417 to $933
$500$1K$2Kfacility $617professional $708

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$691.83
Median
$707.95
Typical High
$776.25
CareFirst
Setting
Professional
Modifier
None
Typical Low
$676.08
Median
$741.31
Typical High
$741.31
Cigna
Setting
Facility
Modifier
None
Typical Low
$501.19
Median
$616.60
Typical High
$1,202.26
Cigna
Setting
Professional
Modifier
None
Typical Low
$489.78
Median
$891.25
Typical High
$2,691.53
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$933.25
Median
$1,122.02
Typical High
$1,412.54
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$467.74
Typical High
$831.76
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$363.08
Median
$371.54
Typical High
$933.25
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$346.74
Median
$354.81
Typical High
$389.05
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$138.04
Median
$141.25
Typical High
$154.88

Where Maryland sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 44th of 51

$692

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.