go back

Mitochondrial DNA Large Deletion Test

Indiana rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$692

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $692 for this service. The price depends on where it is billed: about $562 from a physician practice, and about $933 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$562$372 to $851
FacilityA hospital or hospital-owned outpatient department$933$851 to $1,862

How much rates vary

Facilitymedian $933 · 10th to 90th $741 to $2,818Professionalmedian $562 · 10th to 90th $372 to $1,413
$100$200$500$1K$2K$5Kfacility $933professional $562

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$776.25
Median
$1,412.54
Typical High
$3,467.37
Aetna
Setting
Professional
Modifier
None
Typical Low
$707.95
Median
$776.25
Typical High
$1,412.54
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$741.31
Median
$933.25
Typical High
$2,818.38
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$371.54
Median
$407.38
Typical High
$1,412.54
CareSource
Setting
Facility
Modifier
None
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$1,174.90
Cigna
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$933.25
Typical High
$2,630.27
Cigna
Setting
Professional
Modifier
None
Typical Low
$446.68
Median
$851.14
Typical High
$1,778.28
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$912.01
Median
$1,584.89
Typical High
$2,818.38
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None
Typical Low
$676.08
Median
$794.33
Typical High
$1,445.44
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$562.34
Typical High
$1,122.02
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$371.54
Median
$380.19
Typical High
$707.95
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$151.36
Median
$154.88
Typical High
$281.84

Where Indiana sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 43rd of 51

$692

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.