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Mitochondrial DNA Large Deletion Test

New York rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$851

Typical negotiated rate. In New York, October 2026.

Insurers have agreed to pay about $851 for this service. The price depends on where it is billed: about $794 from a physician practice, and about $1,622 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$794$447 to $1,148
FacilityA hospital or hospital-owned outpatient department$1,622$933 to $2,291

How much rates vary

Facilitymedian $1,622 · 10th to 90th $661 to $2,455Professionalmedian $794 · 10th to 90th $372 to $1,862
$20$100$500$2K$10Kfacility $1,622professional $794

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$724.44
Median
$1,148.15
Typical High
$2,884.03
Aetna
Setting
Professional
Modifier
None
Typical Low
$794.33
Median
$1,148.15
Typical High
$1,148.15
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$2,454.71
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$371.54
Median
$891.25
Typical High
$1,949.84
CDPHP
Setting
Professional
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$933.25
Cigna
Setting
Facility
Modifier
None
Typical Low
$912.01
Median
$1,995.26
Typical High
$2,691.53
Cigna
Setting
Professional
Modifier
None
Typical Low
$562.34
Median
$1,148.15
Typical High
$4,466.84
Emblem Health
Setting
Facility
Modifier
None
Typical Low
$933.25
Median
$1,548.82
Typical High
$2,570.40
Emblem Health
Setting
Professional
Modifier
None
Typical Low
$549.54
Median
$660.69
Typical High
$1,348.96
Excellus BCBS
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$933.25
Typical High
$1,071.52
MVP Health Care
Setting
Facility
Modifier
None
Typical Low
$13.80
Median
$257.04
Typical High
$1,862.09
MVP Health Care
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$645.65
Typical High
$1,949.84
United
Setting
Facility
Modifier
None
Typical Low
$851.14
Median
$933.25
Typical High
$1,174.90
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$446.68
Typical High
$1,412.54
Univera
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$602.56
Typical High
$1,000.00
Univera
Setting
Professional
Modifier
None
Typical Low
$588.84
Median
$891.25
Typical High
$1,071.52
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$398.11
Median
$575.44
Typical High
$575.44
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$158.49
Median
$229.09
Typical High
$229.09

Where New York sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New York· 28th of 51

$851

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.