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Mitochondrial DNA Large Deletion Test

Nationwide rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated July 2026.

Facilitymedian $1,288 · 10th–90th $708$3,8900%20%10th90th$1,288Professionalmedian $813 · 10th–90th $389$1,6980%20%40%10th90th$813$0.0$0.2$2.0$20.0$200.0$2.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$741.31
Median
$1,445.44
Typical High
$3,630.78
Aetna
Setting
Professional
Modifier
Global
Typical Low
$660.69
Median
$794.33
Typical High
$1,380.38
BCBS
Setting
Facility
Modifier
Global
Typical Low
$831.76
Median
$1,258.93
Typical High
$4,168.69
BCBS
Setting
Professional
Modifier
Global
Typical Low
$371.54
Median
$489.78
Typical High
$2,754.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$645.65
Median
$1,778.28
Typical High
$4,073.80
Cigna
Setting
Professional
Modifier
Global
Typical Low
$457.09
Median
$1,096.48
Typical High
$2,238.72
United
Setting
Facility
Modifier
Global
Typical Low
$389.05
Median
$933.25
Typical High
$1,122.02
United
Setting
Professional
Modifier
Global
Typical Low
$389.05
Median
$562.34
Typical High
$1,258.93