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Mitochondrial DNA Large Deletion Test

South Carolina rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated July 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$741

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $741 for this service. The price depends on where it is billed: about $724 from a physician practice, and about $1,318 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$724$724 to $776
FacilityA hospital or hospital-owned outpatient department$1,318$724 to $3,020

How much rates vary

Facilitymedian $1,318 · 10th to 90th $708 to $4,266Professionalmedian $724 · 10th to 90th $562 to $977
$500$1K$2K$5Kfacility $1,318professional $724

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$660.69
Median
$2,290.87
Typical High
$4,466.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$724.44
Median
$724.44
Typical High
$812.83
BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,023.29
Median
$1,174.90
Typical High
$1,288.25
BCBS
Setting
Professional
Modifier
Global
Typical Low
$933.25
Median
$1,000.00
Typical High
$1,318.26
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,778.28
Median
$3,090.30
Typical High
$5,370.32
Cigna
Setting
Professional
Modifier
Global
Typical Low
$426.58
Median
$549.54
Typical High
$1,122.02
Medcost
Setting
Facility
Modifier
Global
Typical Low
$724.44
Median
$870.96
Typical High
$1,230.27
United
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$933.25
Typical High
$1,122.02
United
Setting
Professional
Modifier
Global
Typical Low
$389.05
Median
$562.34
Typical High
$933.25

Where South Carolina sits

The same service costs 2.0 times more in South Dakota than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 46th of 51

$741

SD $1,413DC $708

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.