go back

Mitochondrial DNA Large Deletion Test

South Carolina rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$933

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $933 for this service. The price depends on where it is billed: about $933 from a physician practice, and about $1,175 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$933$562 to $933
FacilityA hospital or hospital-owned outpatient department$1,175$1,000 to $1,950

How much rates vary

Facilitymedian $1,175 · 10th to 90th $794 to $5,129Professionalmedian $933 · 10th to 90th $468 to $1,122
$500$1K$2K$5Kfacility $1,175professional $933

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$724.44
Median
$724.44
Typical High
$724.44
Aetna
Setting
Professional
Modifier
None
Typical Low
$724.44
Median
$724.44
Typical High
$741.31
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$1,023.29
Median
$1,148.15
Typical High
$1,318.26
BCBS South Carolina
Setting
Professional
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$1,071.52
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,778.28
Median
$2,398.83
Typical High
$5,754.40
Cigna
Setting
Professional
Modifier
None
Typical Low
$426.58
Median
$512.86
Typical High
$1,122.02
Medcost
Setting
Facility
Modifier
None
Typical Low
$660.69
Median
$870.96
Typical High
$1,230.27
Medcost
Setting
Professional
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$1,318.26
United
Setting
Facility
Modifier
None
Typical Low
$851.14
Median
$851.14
Typical High
$1,122.02
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$562.34
Typical High
$933.25
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$363.08
Median
$363.08
Typical High
$371.54
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$144.54
Median
$144.54
Typical High
$151.36
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$467.74
Median
$467.74
Typical High
$741.31

Where South Carolina sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 21st of 51

$933

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.