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Mitochondrial DNA Large Deletion Test

Minnesota rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$933

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $933 for this service. The price depends on where it is billed: about $933 from a physician practice, and about $933 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$933$851 to $1,122
FacilityA hospital or hospital-owned outpatient department$933$871 to $2,188

How much rates vary

Facilitymedian $933 · 10th to 90th $661 to $3,631Professionalmedian $933 · 10th to 90th $562 to $1,862
$200$500$1K$2K$5Kfacility $933professional $933

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$870.96
Median
$870.96
Typical High
$870.96
Aetna
Setting
Professional
Modifier
None
Typical Low
$870.96
Median
$870.96
Typical High
$1,122.02
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$229.09
Median
$912.01
Typical High
$933.25
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$741.31
Median
$851.14
Typical High
$933.25
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,862.09
Median
$3,019.95
Typical High
$8,709.64
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,096.48
Median
$1,230.27
Typical High
$1,819.70
Health Partners
Setting
Facility
Modifier
None
Typical Low
$1,778.28
Median
$2,884.03
Typical High
$6,918.31
Health Partners
Setting
Professional
Modifier
None
Typical Low
$1,071.52
Median
$1,071.52
Typical High
$1,778.28
Medica
Setting
Facility
Modifier
None
Typical Low
$933.25
Median
$1,737.80
Typical High
$4,466.84
Medica
Setting
Professional
Modifier
None
Typical Low
$478.63
Median
$977.24
Typical High
$4,677.35
United
Setting
Facility
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$1,122.02
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$851.14
Typical High
$2,089.30
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$436.52
Median
$436.52
Typical High
$436.52
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$177.83
Median
$177.83
Typical High
$177.83
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$436.52
Median
$436.52
Typical High
$562.34
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$177.83
Median
$177.83
Typical High
$223.87

Where Minnesota sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 23rd of 51

$933

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.