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Mitochondrial DNA Large Deletion Test

Connecticut rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$977

Typical negotiated rate. In Connecticut, October 2026.

Insurers have agreed to pay about $977 for this service. Most negotiated rates run $562 to $2,291.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $2,291 · 10th to 90th $933 to $5,495Professionalmedian $617 · 10th to 90th $417 to $3,890
$500$1K$2K$5K$10Kfacility $2,291professional $617

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$1,000.00
Median
$1,148.15
Typical High
$1,148.15
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$1,023.29
Median
$2,511.89
Typical High
$5,888.44
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$407.38
Median
$562.34
Typical High
$4,570.88
Cigna
Setting
Facility
Modifier
None
Typical Low
$616.60
Median
$1,479.11
Typical High
$3,388.44
Cigna
Setting
Professional
Modifier
None
Typical Low
$630.96
Median
$1,174.90
Typical High
$2,089.30
ConnectiCare
Setting
Professional
Modifier
None
Typical Low
$549.54
Median
$933.25
Typical High
$1,258.93
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$562.34
Typical High
$1,202.26
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$575.44
Median
$575.44
Typical High
$575.44
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$229.09
Median
$229.09
Typical High
$229.09

Where Connecticut sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 16th of 51

$977

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.