go back

Mitochondrial DNA Large Deletion Test

Colorado rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$933

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $933 for this service. The price depends on where it is billed: about $646 from a physician practice, and about $2,692 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$646$389 to $933
FacilityA hospital or hospital-owned outpatient department$2,692$1,698 to $3,236

How much rates vary

Facilitymedian $2,692 · 10th to 90th $724 to $4,266Professionalmedian $646 · 10th to 90th $389 to $1,950
$500$1K$2K$5Kfacility $2,692professional $646

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$933.25
Median
$1,949.84
Typical High
$4,365.16
Aetna
Setting
Professional
Modifier
None
Typical Low
$660.69
Median
$707.95
Typical High
$1,148.15
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$1,000.00
Median
$2,818.38
Typical High
$4,265.80
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$645.65
Typical High
$2,089.30
Cigna
Setting
Facility
Modifier
None
Typical Low
$501.19
Median
$1,122.02
Typical High
$2,951.21
Cigna
Setting
Professional
Modifier
None
Typical Low
$436.52
Median
$691.83
Typical High
$1,348.96
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$707.95
Median
$851.14
Typical High
$1,174.90
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$891.25
Median
$1,318.26
Typical High
$1,949.84
Select Health
Setting
Facility
Modifier
None
Typical Low
$933.25
Median
$1,737.80
Typical High
$1,949.84
Select Health
Setting
Professional
Modifier
None
Typical Low
$660.69
Median
$933.25
Typical High
$1,412.54
United
Setting
Facility
Modifier
None
Typical Low
$1,122.02
Median
$1,122.02
Typical High
$1,122.02
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$389.05
Typical High
$691.83
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$354.81
Median
$354.81
Typical High
$575.44
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$141.25
Median
$141.25
Typical High
$229.09

Where Colorado sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 24th of 51

$933

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.