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Mitochondrial DNA Large Deletion Test

Virginia rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$676

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $676 for this service. The price depends on where it is billed: about $631 from a physician practice, and about $1,175 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$631$389 to $741
FacilityA hospital or hospital-owned outpatient department$1,175$933 to $2,188

How much rates vary

Facilitymedian $1,175 · 10th to 90th $794 to $4,571Professionalmedian $631 · 10th to 90th $372 to $1,175
$500$1K$2K$5K$10Kfacility $1,175professional $631

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$707.95
Median
$794.33
Typical High
$2,187.76
Aetna
Setting
Professional
Modifier
None
Typical Low
$707.95
Median
$741.31
Typical High
$794.33
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$4,570.88
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$371.54
Median
$457.09
Typical High
$691.83
CareFirst
Setting
Professional
Modifier
None
Typical Low
$676.08
Median
$741.31
Typical High
$851.14
Cigna
Setting
Facility
Modifier
None
Typical Low
$954.99
Median
$1,548.82
Typical High
$2,398.83
Cigna
Setting
Professional
Modifier
None
Typical Low
$467.74
Median
$691.83
Typical High
$1,584.89
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$891.25
Median
$1,023.29
Typical High
$1,318.26
Medcost
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$933.25
Typical High
$1,258.93
Medcost
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$602.56
Typical High
$933.25
Sentara
Setting
Facility
Modifier
None
Typical Low
$660.69
Median
$1,288.25
Typical High
$10,232.93
Sentara
Setting
Professional
Modifier
None
Typical Low
$741.31
Median
$1,230.27
Typical High
$10,232.93
United
Setting
Facility
Modifier
None
Typical Low
$1,122.02
Median
$1,122.02
Typical High
$1,122.02
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$549.54
Typical High
$1,258.93
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$354.81
Median
$371.54
Typical High
$398.11
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$141.25
Median
$151.36
Typical High
$158.49

Where Virginia sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 45th of 51

$676

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.