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Mitochondrial DNA Large Deletion Test

Missouri rates for HCPCS 81465

A laboratory test that examines the DNA inside mitochondria, the structures that generate energy inside cells, looking for large missing sections. It also reports what proportion of a person's mitochondria carry the change, since this varies from cell to cell and from tissue to tissue.

Rates data updated October 2026.

How much does Mitochondrial DNA Large Deletion Test cost?

$851

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $851 for this service. The price depends on where it is billed: about $724 from a physician practice, and about $1,622 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$724$562 to $1,230
FacilityA hospital or hospital-owned outpatient department$1,622$955 to $3,162

How much rates vary

Facilitymedian $1,622 · 10th to 90th $851 to $4,467Professionalmedian $724 · 10th to 90th $389 to $2,089
$500$1K$2K$5Kfacility $1,622professional $724

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$794.33
Median
$1,202.26
Typical High
$1,737.80
Aetna
Setting
Professional
Modifier
None
Typical Low
$794.33
Median
$812.83
Typical High
$1,071.52
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$4,365.16
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$371.54
Median
$645.65
Typical High
$1,698.24
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$1,288.25
Median
$1,445.44
Typical High
$2,570.40
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$660.69
Median
$933.25
Typical High
$1,778.28
Cigna
Setting
Facility
Modifier
None
Typical Low
$954.99
Median
$1,819.70
Typical High
$2,951.21
Cigna
Setting
Professional
Modifier
None
Typical Low
$446.68
Median
$1,071.52
Typical High
$1,348.96
Medica
Setting
Facility
Modifier
None
Typical Low
$812.83
Median
$1,621.81
Typical High
$4,466.84
Medica
Setting
Professional
Modifier
None
Typical Low
$467.74
Median
$977.24
Typical High
$4,677.35
United
Setting
Facility
Modifier
None
Typical Low
$851.14
Median
$851.14
Typical High
$851.14
United
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$562.34
Typical High
$1,258.93
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$398.11
Median
$398.11
Typical High
$537.03
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$158.49
Median
$162.18
Typical High
$213.80

Where Missouri sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 29th of 51

$851

AK $2,089GA $562

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.