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Light-Activated Drug Treatment for Retina Vessels

North Carolina rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated July 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$309

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $309 for this service. The price depends on where it is billed: about $295 from a physician practice, and about $794 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$295$245 to $407
FacilityA hospital or hospital-owned outpatient department$794$309 to $1,862

How much rates vary

Facilitymedian $794 · 10th to 90th $219 to $5,495Professionalmedian $295 · 10th to 90th $200 to $661
$100.0$200.0$500.0$1.0K$2.0K$5.0K$10.0Kfacility $794professional $295

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$933.25
Typical High
$6,456.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$263.03
Typical High
$588.84
BCBS
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$407.38
Typical High
$851.14
Cigna
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$331.13
Typical High
$537.03
Medcost
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$302.00
Typical High
$512.86
Medcost
Setting
Professional
Modifier
Global
Typical Low
$426.58
Median
$426.58
Typical High
$426.58
United
Setting
Facility
Modifier
Global
Typical Low
$912.01
Median
$2,344.23
Typical High
$4,365.16
United
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$269.15
Typical High
$524.81
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$1,288.25
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$2,041.74
Median
$2,041.74
Typical High
$2,344.23

Where North Carolina sits

The same service costs 3.8 times more in Wyoming than in West Virginia. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

North Carolina $309 · 35th of 51
WY $977WV $257

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.