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Light-Activated Drug Treatment for Retina Vessels

Oklahoma rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated October 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$324

Typical negotiated rate. In Oklahoma, October 2026.

Insurers have agreed to pay about $324 for this service. The price depends on where it is billed: about $282 from a physician practice, and about $1,202 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$282$245 to $355
FacilityA hospital or hospital-owned outpatient department$1,202$407 to $1,905

How much rates vary

Facilitymedian $1,202 · 10th to 90th $295 to $2,512Professionalmedian $282 · 10th to 90th $214 to $1,549
$200$500$1K$2K$5Kfacility $1,202professional $282

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$630.96
Median
$2,511.89
Typical High
$7,585.78
Aetna
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$281.84
Typical High
$302.00
BCBS Oklahoma
Setting
Facility
Modifier
None
Typical Low
$870.96
Median
$1,445.44
Typical High
$2,238.72
BCBS Oklahoma
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$275.42
Typical High
$363.08
Cigna
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$199.53
Typical High
$467.74
Cigna
Setting
Professional
Modifier
None
Typical Low
$234.42
Median
$316.23
Typical High
$354.81
Medica
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$407.38
Typical High
$2,398.83
Medica
Setting
Professional
Modifier
None
Typical Low
$257.04
Median
$1,548.82
Typical High
$2,041.74
United
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$1,148.15
Typical High
$2,454.71
United
Setting
Professional
Modifier
None
Typical Low
$186.21
Median
$245.47
Typical High
$346.74
5 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$112.20
Median
$114.82
Typical High
$147.91
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$45.71
Median
$46.77
Typical High
$58.88
Aetna
Setting
Professional
Modifier
54 · Surgery only
Typical Low
$169.82
Median
$173.78
Typical High
$223.87
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$33.88
Median
$34.67
Typical High
$44.67
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$22.39
Median
$22.91
Typical High
$29.51

Where Oklahoma sits

The same service costs 3.5 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Oklahoma· 26th of 51

$324

AK $832FL $234

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.